Detalhe da pesquisa
1.
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes.
Development
; 150(8)2023 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37102702
2.
Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration.
PLoS Genet
; 14(5): e1007383, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29746474
3.
Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse models.
Neurobiol Dis
; 105: 235-244, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28624415
4.
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome.
Sci Transl Med
; 16(731): eadd6883, 2024 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-38266108
5.
Noggin null allele mice exhibit a microform of holoprosencephaly.
Hum Mol Genet
; 20(20): 4005-15, 2011 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21821669
6.
Genetic dissection of triplicated chromosome 21 orthologs yields varying skeletal traits in Down syndrome model mice.
Dis Model Mech
; 16(4)2023 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36939025
7.
Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation.
Hum Mol Genet
; 19(17): 3457-67, 2010 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20570969
8.
The essential requirement for Runx1 in the development of the sternum.
Dev Biol
; 340(2): 539-46, 2010 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20152828
9.
Maternal iron deficiency perturbs embryonic cardiovascular development in mice.
Nat Commun
; 12(1): 3447, 2021 06 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34103494
10.
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes.
Dis Model Mech
; 14(10)2021 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34477842
11.
Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome.
Bone
; 136: 115367, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32305495
12.
Localization and fate of Fgf10-expressing cells in the adult mouse brain implicate Fgf10 in control of neurogenesis.
Mol Cell Neurosci
; 37(4): 857-68, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18329286
13.
Gene expression dysregulation domains are not a specific feature of Down syndrome.
Nat Commun
; 10(1): 2489, 2019 06 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31171815
14.
Cell fate specification during calvarial bone and suture development.
Dev Biol
; 311(2): 335-46, 2007 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17931618
15.
Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel.
Elife
; 52016 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26765563
16.
Correction: Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel.
Elife
; 92020 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32692312
17.
Alterations to dendritic spine morphology, but not dendrite patterning, of cortical projection neurons in Tc1 and Ts1Rhr mouse models of Down syndrome.
PLoS One
; 8(10): e78561, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24205261
18.
Down syndrome: searching for the genetic culprits.
Dis Model Mech
; 4(5): 586-95, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21878459
19.
Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse.
Cardiovasc Res
; 88(2): 287-95, 2010 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20558441
20.
Evidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrome mouse model.
Dev Dyn
; 238(2): 376-85, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-18773495