Detalhe da pesquisa
1.
Aß and tau prions feature in the neuropathogenesis of Down syndrome.
Proc Natl Acad Sci U S A
; 119(46): e2212954119, 2022 11 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36343257
2.
Mutation analysis of disease causing genes in patients with early onset or familial forms of Alzheimer's disease and frontotemporal dementia.
BMC Genomics
; 23(1): 99, 2022 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35120450
3.
The Amyloid-ß Pathway in Alzheimer's Disease.
Mol Psychiatry
; 26(10): 5481-5503, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34456336
4.
Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease.
Mol Cell Neurosci
; 114: 103641, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34091073
5.
ABBV-0805, a novel antibody selective for soluble aggregated α-synuclein, prolongs lifespan and prevents buildup of α-synuclein pathology in mouse models of Parkinson's disease.
Neurobiol Dis
; 161: 105543, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34737044
6.
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Nature
; 526(7573): 443-7, 2015 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26322584
7.
Structural heterogeneity and intersubject variability of Aß in familial and sporadic Alzheimer's disease.
Proc Natl Acad Sci U S A
; 115(4): E782-E791, 2018 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-29311311
8.
Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease.
Am J Hum Genet
; 98(6): 1208-1219, 2016 Jun 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27231129
9.
The Aß protofibril selective antibody mAb158 prevents accumulation of Aß in astrocytes and rescues neurons from Aß-induced cell death.
J Neuroinflammation
; 15(1): 98, 2018 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-29592816
10.
Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers.
Acta Neuropathol
; 136(1): 41-56, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29934873
11.
No association between CALHM1 and Alzheimer's disease risk.
Cell
; 135(6): 993-4; author reply 994-6, 2008 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-19070563
12.
A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging.
Neuroimage
; 148: 55-63, 2017 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28069541
13.
Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes.
J Neuroinflammation
; 14(1): 241, 2017 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-29228971
14.
Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells.
Biol Proced Online
; 19: 11, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28932173
15.
Cellular Uptake of α-Synuclein Oligomer-Selective Antibodies is Enhanced by the Extracellular Presence of α-Synuclein and Mediated via Fcγ Receptors.
Cell Mol Neurobiol
; 37(1): 121-131, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26961542
16.
Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein.
Cell Mol Neurobiol
; 37(7): 1217-1226, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28028735
17.
Predicting Cognitive Decline across Four Decades in Mutation Carriers and Non-carriers in Autosomal-Dominant Alzheimer's Disease.
J Int Neuropsychol Soc
; 23(3): 195-203, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28079014
18.
Serial propagation of distinct strains of Aß prions from Alzheimer's disease patients.
Proc Natl Acad Sci U S A
; 111(28): 10323-8, 2014 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24982139
19.
Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.
J Biol Chem
; 290(24): 14904-14, 2015 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25869127
20.
Age-related somatic structural changes in the nuclear genome of human blood cells.
Am J Hum Genet
; 90(2): 217-28, 2012 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-22305530