Detalhe da pesquisa
1.
Contribution of APOE Genetic Variants to Dyslipidemia.
Arterioscler Thromb Vasc Biol
; 43(6): 1066-1077, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37051929
2.
Predictive Modeling and Structure Analysis of Genetic Variants in Familial Hypercholesterolemia: Implications for Diagnosis and Protein Interaction Studies.
Curr Atheroscler Rep
; 25(11): 839-859, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37847331
3.
Leu22_Leu23 Duplication at the Signal Peptide of PCSK9 Promotes Intracellular Degradation of LDLr and Autosomal Dominant Hypercholesterolemia.
Arterioscler Thromb Vasc Biol
; 42(7): e203-e216, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35510551
4.
Cardiovascular Disease, Atherosclerosis and Familial Hypercholesterolemia: From Molecular Mechanisms Causing Pathogenicity to New Therapeutic Approaches.
Int J Mol Sci
; 24(8)2023 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37108820
5.
Functional Characterization of p.(Arg160Gln) PCSK9 Variant Accidentally Found in a Hypercholesterolemic Subject.
Int J Mol Sci
; 24(4)2023 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36834740
6.
Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis Model.
Small
; 18(13): e2105915, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35156292
7.
Pathophysiology of Atherosclerosis.
Int J Mol Sci
; 23(6)2022 Mar 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35328769
8.
A Systematic Approach to Assess the Activity and Classification of PCSK9 Variants.
Int J Mol Sci
; 22(24)2021 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34948399
9.
Pathophysiology of Type 2 Diabetes Mellitus.
Int J Mol Sci
; 21(17)2020 Aug 30.
Artigo
Inglês
| MEDLINE | ID: mdl-32872570
10.
Statin Treatment-Induced Development of Type 2 Diabetes: From Clinical Evidence to Mechanistic Insights.
Int J Mol Sci
; 21(13)2020 Jul 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32630698
11.
Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing.
Polymers (Basel)
; 16(7)2024 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38611244
12.
Extrusion-Based 3D Printing of Photocrosslinkable Chitosan Inks.
Gels
; 10(2)2024 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38391456
13.
OptiMo-LDLr: An Integrated In Silico Model with Enhanced Predictive Power for LDL Receptor Variants, Unraveling Hot Spot Pathogenic Residues.
Adv Sci (Weinh)
; 11(13): e2305177, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38258479
14.
Lipoprotein(a) in hereditary hypercholesterolemia: Influence of the genetic cause, defective gene and type of mutation.
Atherosclerosis
; 349: 211-218, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34456049
15.
Molecular mechanisms of lipotoxicity-induced pancreatic ß-cell dysfunction.
Int Rev Cell Mol Biol
; 359: 357-402, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33832653
16.
MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants.
JACC Basic Transl Sci
; 6(11): 815-827, 2021 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-34869944
17.
Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR.
Sci Rep
; 10(1): 1727, 2020 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32015373
18.
Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition.
Biomedicines
; 8(10)2020 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-32977626
19.
The Arg499His gain-of-function mutation in the C-terminal domain of PCSK9.
Atherosclerosis
; 289: 162-172, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31518966