Detalhe da pesquisa
1.
The Prohibitin-Binding Compound Fluorizoline Activates the Integrated Stress Response through the eIF2α Kinase HRI.
Int J Mol Sci
; 24(9)2023 Apr 29.
Artigo
Inglês
| MEDLINE | ID: mdl-37175767
2.
Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds.
Angew Chem Int Ed Engl
; 62(41): e202303889, 2023 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37191208
3.
A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death.
Angew Chem Int Ed Engl
; 61(5): e202113020, 2022 01 26.
Artigo
Inglês
| MEDLINE | ID: mdl-34762762
4.
Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.
Apoptosis
; 26(1-2): 83-95, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33387147
5.
Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines.
Int J Mol Sci
; 22(11)2021 Jun 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34204139
6.
Extended Multicomponent Reactions with Indole Aldehydes: Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor.
Angew Chem Int Ed Engl
; 60(5): 2603-2608, 2021 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33048416
7.
Selectivity in multiple multicomponent reactions: types and synthetic applications.
Beilstein J Org Chem
; 15: 521-534, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30873236
8.
Multiple Multicomponent Reactions: Unexplored Substrates, Selective Processes, and Versatile Chemotypes in Biomedicine.
Chemistry
; 24(54): 14513-14521, 2018 Sep 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29974986
9.
Recent advances of the Povarov reaction in medicinal chemistry.
Drug Discov Today Technol
; 29: 71-79, 2018 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-30471676
10.
Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases.
Molecules
; 23(1)2018 Jan 16.
Artigo
Inglês
| MEDLINE | ID: mdl-29337878
11.
Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis.
Ann Rheum Dis
; 76(9): 1624-1634, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28606962
12.
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax.
Haematologica
; 102(9): 1587-1593, 2017 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28619845
13.
Synthesis, pharmacological evaluation and molecular docking of pyranopyrazole-linked 1,4-dihydropyridines as potent positive inotropes.
Mol Divers
; 21(3): 533-546, 2017 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-28444482
14.
Modern Synthetic Avenues for the Preparation of Functional Fluorophores.
Angew Chem Int Ed Engl
; 56(14): 3758-3769, 2017 03 27.
Artigo
Inglês
| MEDLINE | ID: mdl-27907246
15.
Electrophilic, Activation-Free Fluorogenic Reagent for Labeling Bioactive Amines.
Bioconjug Chem
; 27(6): 1430-4, 2016 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27248580
16.
Constrained Cyclopeptides: Biaryl Formation through Pd-Catalyzed C-H Activation in Peptides-Structural Control of the Cyclization vs. Cyclodimerization Outcome.
Chemistry
; 22(37): 13114-9, 2016 Sep 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27490359
17.
Enhanced antimicrobial activity of a peptide derived from human lysozyme by arylation of its tryptophan residues.
J Pept Sci
; 22(2): 123-8, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26785822
18.
Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.
Angew Chem Int Ed Engl
; 55(31): 8994-8, 2016 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-27314630
19.
A trifluorinated thiazoline scaffold leading to pro-apoptotic agents targeting prohibitins.
Angew Chem Int Ed Engl
; 53(38): 10150-4, 2014 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25196378
20.
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations.
Beilstein J Org Chem
; 10: 12-7, 2014 Jan 06.
Artigo
Inglês
| MEDLINE | ID: mdl-24454559