Detalhe da pesquisa
1.
Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction.
J Biol Chem
; 298(12): 102625, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36306823
2.
Tralesinidase Alfa Enzyme Replacement Therapy Prevents Disease Manifestations in a Canine Model of Mucopolysaccharidosis Type IIIB.
J Pharmacol Exp Ther
; 382(3): 277-286, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35717448
3.
Intracerebroventricular enzyme replacement therapy with ß-galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice.
J Biol Chem
; 295(39): 13532-13555, 2020 09 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31481471
4.
Biochemical evaluation of intracerebroventricular rhNAGLU-IGF2 enzyme replacement therapy in neonatal mice with Sanfilippo B syndrome.
Mol Genet Metab
; 133(2): 185-192, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33839004
5.
Characterization of disease-specific chondroitin sulfate nonreducing end accumulation in mucopolysaccharidosis IVA.
Glycobiology
; 30(7): 433-445, 2020 07 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31897472
6.
N-glycolyl groups of nonhuman chondroitin sulfates survive in ancient fossils.
Proc Natl Acad Sci U S A
; 114(39): E8155-E8164, 2017 09 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28893995
7.
Sonic hedgehog processing and release are regulated by glypican heparan sulfate proteoglycans.
J Cell Sci
; 128(12): 2374-85, 2015 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25967551
8.
Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo.
J Virol
; 90(1): 412-20, 2016 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26491162
9.
Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB.
Proc Natl Acad Sci U S A
; 111(41): 14870-5, 2014 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25267636
10.
A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3).
FASEB J
; 29(7): 2993-3002, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25868729
11.
Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice.
Proc Natl Acad Sci U S A
; 109(26): 10310-5, 2012 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-22689975
12.
Glycan-based biomarkers for mucopolysaccharidoses.
Mol Genet Metab
; 111(2): 73-83, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23958290
13.
Intra-articular enzyme replacement therapy with rhIDUA is safe, well-tolerated, and reduces articular GAG storage in the canine model of mucopolysaccharidosis type I.
Mol Genet Metab
; 112(4): 286-93, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24951454
14.
Disease-specific non-reducing end carbohydrate biomarkers for mucopolysaccharidoses.
Nat Chem Biol
; 8(2): 197-204, 2012 Jan 08.
Artigo
Inglês
| MEDLINE | ID: mdl-22231271
15.
Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice.
Arterioscler Thromb Vasc Biol
; 33(9): 2065-74, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23846497
16.
Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamine.
J Biol Chem
; 287(34): 28898-916, 2012 Aug 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22692203
17.
A genetic model of substrate reduction therapy for mucopolysaccharidosis.
J Biol Chem
; 287(43): 36283-90, 2012 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-22952226
18.
Secondary storage of dermatan sulfate in Sanfilippo disease.
J Biol Chem
; 286(9): 6955-62, 2011 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-21193389
19.
Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.
J Biol Chem
; 286(1): 737-45, 2011 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-20974861
20.
Differential effects of murine and human factor X on adenovirus transduction via cell-surface heparan sulfate.
J Biol Chem
; 286(28): 24535-43, 2011 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21596747