Pesquisa | Secretaria de Estado da Saúde

1.

Identification of a ß-arrestin-biased negative allosteric modulator for the ß₂-adrenergic receptor.

Ippolito, Michael; De Pascali, Francesco; Hopfinger, Nathan; Komolov, Konstantin E; Laurinavichyute, Daniela; Reddy, Poli Adi Narayana; Sakkal, Leon A; Rajkowski, Kyle Z; Nayak, Ajay P; Lee, Justin; Lee, Jordan; Cao, Gaoyuan; Donover, Preston S; Reichman, Melvin; An, Steven S; Salvino, Joseph M; Penn, Raymond B; Armen, Roger S; Scott, Charles P; Benovic, Jeffrey L.

Proc Natl Acad Sci U S A ; 120(31): e2302668120, 2023 08.

Artigo Inglês | MEDLINE | ID: mdl-37490535

2.

Single-neuron bursts encode pathological oscillations in subcortical nuclei of patients with Parkinson's disease and essential tremor.

Scherer, Maximilian; Steiner, Leon A; Kalia, Suneil K; Hodaie, Mojgan; Kühn, Andrea A; Lozano, Andres M; Hutchison, William D; Milosevic, Luka.

Proc Natl Acad Sci U S A ; 119(35): e2205881119, 2022 08 30.

Artigo Inglês | MEDLINE | ID: mdl-36018837

3.

Distinct Inflammatory Phenotypes are associated with subclinical and clinical Cardiovascular disease in People living with HIV.

McGettrick, P; Tinago, W; O'Brien, J; Miles, S; Lawler, L; Garcia-Leon, A; Mahon, N; Lambert, J; Sheehan, G; Landay, A; Sabin, C A; Cotter, A G; Mallon, P W G.

J Infect Dis ; 2024 Jan 12.

Artigo Inglês | MEDLINE | ID: mdl-38214571

4.

What Is a Meaningful Difference When Using Infarct Volume as the Primary Outcome?: Results From the HERMES Database.

Rinkel, Leon A; Ospel, Johanna M; Brown, Scott B; Campbell, Bruce C V; Dippel, Diederik W J; Demchuk, Andrew M; Majoie, Charles B L M; Mitchell, Peter J; Bracard, Serge; Guillemin, Francis; Jovin, Tudor G; Muir, Keith W; White, Philip; Saver, Jeffrey L; Hill, Michael D; Goyal, Mayank.

Stroke ; 55(4): 866-873, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38440891

5.

Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials.

Majoie, Charles B; Cavalcante, Fabiano; Gralla, Jan; Yang, Pengfei; Kaesmacher, Johannes; Treurniet, Kilian M; Kappelhof, Manon; Yan, Bernard; Suzuki, Kentaro; Zhang, Yongwei; Li, Fengli; Morimoto, Masafumi; Zhang, Lei; Miao, Zhongrong; Rinkel, Leon A; Huang, Jiacheng; Otsuka, Toshiaki; Wang, Shouchun; Davis, Stephen; Cognard, Christophe; Hong, Bo; Coutinho, Jonathan M; Song, Jiaxing; Chen, Wenhuo; Emmer, Bart J; Eker, Omer; Zhang, Liyong; Dobrocky, Tomas; Nguyen, Huy-Thang; Bush, Steven; Peng, Ya; LeCouffe, Natalie E; Takeuchi, Masataka; Han, Hongxing; Matsumaru, Yuji; Strbian, Daniel; Lingsma, Hester F; Nieboer, Daan; Yang, Qingwu; Meinel, Thomas; Mitchell, Peter; Kimura, Kazumi; Zi, Wenjie; Nogueira, Raul G; Liu, Jianmin; Roos, Yvo B; Fischer, Urs.

Lancet ; 402(10406): 965-974, 2023 09 16.

Artigo Inglês | MEDLINE | ID: mdl-37640037

6.

Dexamethasone and Surgical-Site Infection.

Corcoran, Tomás B; Myles, Paul S; Forbes, Andrew B; Cheng, Allen C; Bach, Leon A; O'Loughlin, Edmond; Leslie, Kate; Chan, Matthew T V; Story, David; Short, Timothy G; Martin, Catherine; Coutts, Pauline; Ho, Kwok M.

N Engl J Med ; 384(18): 1731-1741, 2021 05 06.

Artigo Inglês | MEDLINE | ID: mdl-33951362

7.

A Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke.

LeCouffe, Natalie E; Kappelhof, Manon; Treurniet, Kilian M; Rinkel, Leon A; Bruggeman, Agnetha E; Berkhemer, Olvert A; Wolff, Lennard; van Voorst, Henk; Tolhuisen, Manon L; Dippel, Diederik W J; van der Lugt, Aad; van Es, Adriaan C G M; Boiten, Jelis; Lycklama À Nijeholt, Geert J; Keizer, Koos; Gons, Rob A R; Yo, Lonneke S F; van Oostenbrugge, Robert J; van Zwam, Wim H; Roozenbeek, Bob; van der Worp, H Bart; Lo, Rob T H; van den Wijngaard, Ido R; de Ridder, Inger R; Costalat, Vincent; Arquizan, Caroline; Lemmens, Robin; Demeestere, Jelle; Hofmeijer, Jeannette; Martens, Jasper M; Schonewille, Wouter J; Vos, Jan-Albert; Uyttenboogaart, Maarten; Bokkers, Reinoud P H; van Tuijl, Julia H; Kortman, Hans; Schreuder, Floris H B M; Boogaarts, Hieronymus D; de Laat, Karlijn F; van Dijk, Lukas C; den Hertog, Heleen M; van Hasselt, Boudewijn A A M; Brouwers, Paul J A M; Bulut, Tomas; Remmers, Michel J M; van Norden, Anouk; Imani, Farshad; Rozeman, Anouk D; Elgersma, Otto E H; Desfontaines, Philippe.

N Engl J Med ; 385(20): 1833-1844, 2021 11 11.

Artigo Inglês | MEDLINE | ID: mdl-34758251

8.

Geographical similarity and differences in the burden and genetic predisposition of NAFLD.

Yip, Terry Cheuk-Fung; Vilar-Gomez, Eduardo; Petta, Salvatore; Yilmaz, Yusuf; Wong, Grace Lai-Hung; Adams, Leon A; de Lédinghen, Victor; Sookoian, Silvia; Wong, Vincent Wai-Sun.

Hepatology ; 77(4): 1404-1427, 2023 04 01.

Artigo Inglês | MEDLINE | ID: mdl-36062393

9.

Predicting liver-related events in NAFLD: A predictive model.

Calzadilla-Bertot, Luis; Jeffrey, Gary P; Wang, Zhengyi; Huang, Yi; Garas, George; Wallace, Michael; de Boer, Bastiaan; George, Jacob; Eslam, Mohammed; Phu, Amy; Ampuero, Javier; Lucena Valera, Ana; Romero-Gómez, Manuel; Aller de la Fuente, Rocio; Adams, Leon A.

Hepatology ; 78(4): 1240-1251, 2023 10 01.

Artigo Inglês | MEDLINE | ID: mdl-36994693

10.

Leaf hydraulic properties of Antarctic plants: effects of growth temperature and its coordination with photosynthesis.

Sáez, Patricia L; Vallejos, Valentina; Sancho-Knapik, Domingo; Cavieres, Lohengrin A; Ramírez, Constanza F; Bravo, León A; Javier Peguero-Pina, José; Gil-Pelegrín, Eustaquio; Galmés, Jeroni.

J Exp Bot ; 75(7): 2013-2026, 2024 Mar 27.

Artigo Inglês | MEDLINE | ID: mdl-38173309

11.

The diabetes management experiences questionnaire: Psychometric validation among adults with type 1 diabetes.

Hendrieckx, Christel; Husin, Hanafi M; Russell-Green, Sienna; Halliday, Jennifer A; Lam, Benjamin; Trawley, Steven; McAuley, Sybil A; Bach, Leon A; Burt, Morton G; Cohen, Neale D; Colman, Peter G; Holmes-Walker, D Jane; Jenkins, Alicia J; Lee, Melissa H; McCallum, Roland W; Stranks, Steve N; Sundararajan, Vijaya; Jones, Tim W; O'Neal, David N; Speight, Jane.

Diabet Med ; 41(3): e15195, 2024 Mar.

Artigo Inglês | MEDLINE | ID: mdl-37562414

12.

Electrical Chain Rearrangement: What Happens When Polymers in Brushes Have a Charge Gradient?

Smook, Leon A; de Beer, Sissi.

Langmuir ; 40(8): 4142-4151, 2024 Feb 27.

Artigo Inglês | MEDLINE | ID: mdl-38355408

13.

Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions.

Neumann, Wolf-Julian; Steiner, Leon A; Milosevic, Luka.

Brain ; 146(11): 4456-4468, 2023 11 02.

Artigo Inglês | MEDLINE | ID: mdl-37450573

14.

The First Comprehensive Chemical Profiling of Vachellia gummifera (Willd.) Kyal. & Boatwr., a Plant with Medicinal Value.

Kisiriko, Musa; Noleto-Dias, Clarice; Bitchagno, Gabin T M; Naboulsi, Imane; Anastasiadi, Maria; Terry, Leon A; Sobeh, Mansour; Beale, Michael H; Ward, Jane L.

Chem Biodivers ; : e202400396, 2024 Mar 19.

Artigo Inglês | MEDLINE | ID: mdl-38501581

15.

Modeling Instantaneous Firing Rate of Deep Brain Stimulation Target Neuronal Ensembles in the Basal Ganglia and Thalamus.

Tian, Yupeng; Murphy, Matthew J H; Steiner, Leon A; Kalia, Suneil K; Hodaie, Mojgan; Lozano, Andres M; Hutchison, William D; Popovic, Milos R; Milosevic, Luka; Lankarany, Milad.

Neuromodulation ; 27(3): 464-475, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-37140523

16.

Role of cardiac computed tomography in hyperacute stroke assessment.

Tomari, Shinya; Chew, Beng Lim Alvin; Soans, Barry; Ai-Hadethi, Sinan; Ottavi, Thomas; Lillicrap, Thomas; Kashida, Yumi Tomari; Ostman, Cecilia; Levi, Christopher R; Parsons, Mark W; Wu, Teddy Y; Rinkel, Leon A; Coutinho, Jonathan M; Garcia-Esperon, Carlos; Spratt, Neil J.

J Stroke Cerebrovasc Dis ; 33(1): 107470, 2024 Jan.

Artigo Inglês | MEDLINE | ID: mdl-38029458

17.

Exposure to benzene and other hydrocarbons and risk of bladder cancer among male offshore petroleum workers.

Shala, Nita K; Stenehjem, Jo S; Babigumira, Ronnie; Liu, Fei-Chih; Berge, Leon A M; Silverman, Debra T; Friesen, Melissa C; Rothman, Nathaniel; Lan, Qing; Hosgood, H Dean; Samuelsen, Sven O; Bråtveit, Magne; Kirkeleit, Jorunn; Andreassen, Bettina K; Veierød, Marit B; Grimsrud, Tom K.

Br J Cancer ; 129(5): 838-851, 2023 09.

Artigo Inglês | MEDLINE | ID: mdl-37464024

18.

Validation of the Blood Test MACK-3 for the Noninvasive Diagnosis of Fibrotic Nonalcoholic Steatohepatitis: An International Study With 1924 Patients.

Canivet, Clémence M; Zheng, Ming-Hua; Qadri, Sami; Vonghia, Luisa; Chuah, Kee-Huat; Costentin, Charlotte; George, Jacob; Armandi, Angelo; Adams, Leon A; Lange, Naomi F; Blanchet, Odile; Moal, Valérie; Younes, Ramy; Roux, Marine; Chan, Wah-Kheong; Sturm, Nathalie; Eslam, Mohammed; Bugianesi, Elisabetta; Wang, Zhengyi; Dufour, Jean-François; Francque, Sven; Yki-Järvinen, Hannele; Zheng, Kenneth I; Boursier, Jérôme.

Clin Gastroenterol Hepatol ; 21(12): 3097-3106.e10, 2023 11.

Artigo Inglês | MEDLINE | ID: mdl-37031715

19.

Nivolumab versus placebo as adjuvant therapy for resected stage III melanoma: a propensity weighted indirect treatment comparison and number needed to treat analysis for recurrence-free survival and overall survival.

Weber, Jeffrey S; Poretta, Tayla; Stwalley, Brian D; Sakkal, Leon A; Du, Ella X; Wang, Travis; Chen, Yan; Wang, Yan; Betts, Keith A; Shoushtari, Alexander N.

Cancer Immunol Immunother ; 72(4): 945-954, 2023 Apr.

Artigo Inglês | MEDLINE | ID: mdl-36197494

20.

Development, implementation and evaluation of a multinational FLS mentorship programme in Latin America.

Javaid, M Kassim; Calo, M; Wullich, S; Mohsin, Z; Osorio, E Castro; Orjuela, A Medina; Unigarro, C Arteaga; Mendez-Sanchez, L; Naranjo, J Torres; Vieira, L Tikle; Tutiya, K Kuraoka; Inacio, A Manoel; de Leon, A Olascoaga-Gomez; García, J Carlos Viveros; Habib, C; Subies, F; Guyot, J P; Diehl, M; Carabelli, G; Soulie, A; Cooper, C.

Osteoporos Int ; 34(11): 1881-1891, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37418151

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