Detalhe da pesquisa
1.
The Engineered Lysin, CF-370, is Active Against Antibiotic-Resistant Gram-Negative Pathogens In vitro and Synergizes with Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.
J Infect Dis
; 2024 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38366561
2.
Evaluation of the distribution and excretion of [14C]-inclisiran following single subcutaneous administration in cynomolgus monkeys.
Toxicol Appl Pharmacol
; 443: 115978, 2022 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35288146
3.
Exebacase in Addition to Daptomycin against MRSA.
Antimicrob Agents Chemother
; 65(11): e0012821, 2021 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34398668
4.
Efficacy assessment of lysin CF-296 in addition to daptomycin or vancomycin against Staphylococcus aureus in the murine thigh infection model.
J Antimicrob Chemother
; 76(10): 2622-2628, 2021 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34223628
5.
Effect of the Lysin Exebacase on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis as Determined by Echocardiography.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
Inglês
| MEDLINE | ID: mdl-32340988
6.
Exebacase in Addition to Daptomycin Is More Active than Daptomycin or Exebacase Alone in Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31358593
7.
Toxicologic and Inhibitory Receptor Actions of the Etomidate Analog ABP-700 and Its Metabolite CPM-Acid.
Anesthesiology
; 131(2): 287-304, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31166238
8.
Corrigendum to "Evaluation of the distribution and excretion of [14C]-inclisiran following single subcutaneous administration in cynomolgus monkeys" [Toxicology and Applied Pharmacology 443 (2022) 115978].
Toxicol Appl Pharmacol
; 451: 116144, 2022 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35780943
9.
Activity of Lysin CF-296 Alone and in Addition to Daptomycin in a Rat Model of Experimental Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33722889
10.
Oritavancin Pharmacokinetics and Bone Penetration in Rabbits.
Antimicrob Agents Chemother
; 59(10): 6501-5, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26239977
11.
In vitro activity of exebacase against methicillin-resistant Staphylococcus aureus biofilms on orthopedic Kirschner wires.
BMC Res Notes
; 16(1): 209, 2023 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37697424
12.
The N-Acetylgalactosamine-conjugated small interfering RNA inclisiran can be coadministered safely with atorvastatin in cynomolgus monkeys resulting in additive low-density lipoprotein cholesterol reductions.
Pharmacol Res Perspect
; 11(2): e01080, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37021909
13.
Oritavancin does not induce Clostridium difficile germination and toxin production in hamsters or a human gut model.
J Antimicrob Chemother
; 67(12): 2919-26, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22899803
14.
Locally delivered antistaphylococcal lysin exebacase or CF-296 is active in methicillin-resistant Staphylococcus aureus implant-associated osteomyelitis.
J Bone Jt Infect
; 7(4): 169-175, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36032801
15.
Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.
Bioorg Med Chem
; 16(20): 9217-29, 2008 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18815051
16.
Identification of in vivo essential genes from Pseudomonas aeruginosa by PCR-based signature-tagged mutagenesis.
FEMS Microbiol Lett
; 210(1): 73-80, 2002 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-12023080
17.
Identification of novel pathogenicity genes by PCR signature-tagged mutagenesis and related technologies.
Methods Mol Biol
; 266: 289-304, 2004.
Artigo
Inglês
| MEDLINE | ID: mdl-15148424
18.
Polymerase chain reaction-based signature-tagged mutagenesis.
Methods Mol Biol
; 182: 127-37, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-11768960
19.
PCR screening in signature-tagged mutagenesis of essential genes.
Methods Mol Biol
; 192: 225-34, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-12494654
20.
Linking bisphosphonates to the free amino groups in fluoroquinolones: preparation of osteotropic prodrugs for the prevention of osteomyelitis.
J Med Chem
; 51(21): 6955-69, 2008 Nov 13.
Artigo
Inglês
| MEDLINE | ID: mdl-18834106