Detalhe da pesquisa
1.
Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs.
J Enzyme Inhib Med Chem
; 31(4): 551-62, 2016 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26024288
2.
Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.
Cell Chem Biol
; 31(4): 729-742.e13, 2024 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38492573
3.
Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
ACS Chem Biol
; 18(5): 1124-1135, 2023 05 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37144894
4.
Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases.
ACS Infect Dis
; 9(11): 2190-2201, 2023 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37820055
5.
SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors.
Bioorg Med Chem Lett
; 22(24): 7653-8, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23127890
6.
Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.
Int J Parasitol
; 52(11): 733-744, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35447149
7.
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
PLoS One
; 16(3): e0241738, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33760815
8.
Identification and Characterization of Novel Bronchodilator Agonists Acting at Human Airway Smooth Muscle Cell TAS2R5.
ACS Pharmacol Transl Sci
; 3(6): 1069-1075, 2020 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33344890
9.
Characterization of Arylalkylamine N-Acyltransferase from Tribolium castaneum: An Investigation into a Potential Next-Generation Insecticide Target.
ACS Chem Biol
; 15(2): 513-523, 2020 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31967772
10.
Binding-based proteomic profiling and the fatty acid amides.
Trends Res
; 1(4)2018 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-30775690
11.
Enantioselective Total Synthesis of Cannabinoids-A Route for Analogue Development.
Org Lett
; 20(2): 381-384, 2018 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29293352
12.
Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.
ACS Chem Biol
; 13(8): 2288-2299, 2018 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29893552
13.
Synthesis and Activity of a New Series of Antileishmanial Agents.
ACS Med Chem Lett
; 8(8): 797-801, 2017 Aug 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28835791
14.
Identification of a Hit Series of Antileishmanial Compounds through the Use of Mixture-Based Libraries.
ACS Med Chem Lett
; 8(8): 802-807, 2017 Aug 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28835792
15.
Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine.
Sci Rep
; 7(1): 13432, 2017 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-29044148
16.
Synthesis of the phorboxazoles-potent, architecturally novel marine natural products.
J Antibiot (Tokyo)
; 69(4): 220-52, 2016 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26956795
17.
Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).
J Med Chem
; 56(6): 2218-34, 2013 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23394126
18.
Discovery of a novel class of potent and orally bioavailable sphingosine 1-phosphate receptor 1 antagonists.
J Med Chem
; 55(3): 1368-81, 2012 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22214363
19.
Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors.
J Med Chem
; 55(11): 5467-82, 2012 Jun 14.
Artigo
Inglês
| MEDLINE | ID: mdl-22548342
20.
Enantiospecific Total Synthesis of the Potent Antitumor Macrolides Cryptophycins 1 and 8.
J Org Chem
; 62(21): 7098-7099, 1997 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-11671811