Detalhe da pesquisa
1.
The role of globins in cardiovascular physiology.
Physiol Rev
; 102(2): 859-892, 2022 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34486392
2.
Base editing of haematopoietic stem cells rescues sickle cell disease in mice.
Nature
; 595(7866): 295-302, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34079130
3.
Loss of miR-144/451 alleviates ß-thalassemia by stimulating ULK1-mediated autophagy of free α-globin.
Blood
; 142(10): 918-932, 2023 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37339583
4.
Neuroglobin effectively halts vision loss in Harlequin mice at an advanced stage of optic nerve degeneration.
Neurobiol Dis
; 159: 105483, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34400304
5.
Regulation of gene expression by miR-144/451 during mouse erythropoiesis.
Blood
; 133(23): 2518-2528, 2019 06 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30971389
6.
miR-144/451 represses the LKB1/AMPK/mTOR pathway to promote red cell precursor survival during recovery from acute anemia.
Haematologica
; 103(3): 406-416, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29269522
7.
Neuroglobin gene therapy prevents optic atrophy and preserves durably visual function in Harlequin mice.
Mol Ther
; 22(6): 1096-1109, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24622090
8.
Neuroglobins, pivotal proteins associated with emerging neural systems and precursors of metazoan globin diversity.
J Biol Chem
; 288(10): 6957-67, 2013 Mar 08.
Artigo
Inglês
| MEDLINE | ID: mdl-23288852
9.
Neuroglobin involvement in visual pathways through the optic nerve.
Biochim Biophys Acta
; 1834(9): 1772-8, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23639750
10.
The crystal structure of wild-type human brain neuroglobin reveals flexibility of the disulfide bond that regulates oxygen affinity.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 4): 1005-14, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24699645
11.
Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity.
Biochim Biophys Acta
; 1823(12): 2261-73, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23036890
12.
Downregulation of apoptosis-inducing factor in Harlequin mice induces progressive and severe optic atrophy which is durably prevented by AAV2-AIF1 gene therapy.
Brain
; 135(Pt 1): 35-52, 2012 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-22120150
13.
Redox-Regulation of α-Globin in Vascular Physiology.
Antioxidants (Basel)
; 11(1)2022 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35052663
14.
Endothelial alpha globin is a nitrite reductase.
Nat Commun
; 13(1): 6405, 2022 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36302779
15.
Heme ligand binding properties and intradimer interactions in the full-length sensor protein dos from Escherichia coli and its isolated heme domain.
J Biol Chem
; 284(52): 36146-36159, 2009 Dec 25.
Artigo
Inglês
| MEDLINE | ID: mdl-19864414
16.
Pseudo-merohedral twinning in monoclinic crystals of wild-type human brain neuroglobin.
Acta Crystallogr D Biol Crystallogr
; 65(Pt 4): 388-92, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19307722
17.
Ancestral ß-globin gene haplotypes modify ß-thalassemia severity in a mouse model.
Blood Adv
; 2024 Mar 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38536944
18.
The autophagy-activating kinase ULK1 mediates clearance of free α-globin in ß-thalassemia.
Sci Transl Med
; 11(506)2019 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31434755
19.
Ultrafast heme-residue bond formation in six-coordinate heme proteins: implications for functional ligand exchange.
Biochemistry
; 47(21): 5718-23, 2008 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-18454557
20.
Expression, purification, and crystallization of neuro- and cytoglobin.
Methods Enzymol
; 436: 341-57, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18237642