Detalhe da pesquisa
1.
Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Cell
; 157(2): 472-485, 2014 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-24725412
2.
LC3B drives transcription-associated homologous recombination via direct interaction with R-loops.
Nucleic Acids Res
; 52(9): 5088-5106, 2024 May 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38412240
3.
Decoding the temporal nature of brain GR activity in the NFκB signal transition leading to depressive-like behavior.
Mol Psychiatry
; 26(9): 5087-5096, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33483691
4.
Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.
Proc Natl Acad Sci U S A
; 115(7): 1635-1640, 2018 02 13.
Artigo
Inglês
| MEDLINE | ID: mdl-29386392
5.
GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules.
Genes Dev
; 25(18): 1968-81, 2011 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21937714
6.
Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration.
Proc Natl Acad Sci U S A
; 112(37): 11696-701, 2015 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26324925
7.
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.
Proc Natl Acad Sci U S A
; 108(34): 14103-8, 2011 Aug 23.
Artigo
Inglês
| MEDLINE | ID: mdl-21825151
8.
Suppression of Glioblastoma Stem Cell Potency and Tumor Growth via LRRK2 Inhibition.
Int J Stem Cells
; 2024 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38584542
9.
Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models.
Hum Mol Genet
; 20(20): 3933-42, 2011 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21768216
10.
LRRK2 at the Crossroad of Aging and Parkinson's Disease.
Genes (Basel)
; 12(4)2021 03 29.
Artigo
Inglês
| MEDLINE | ID: mdl-33805527
11.
Modified Protocol to Enable the Study of Hemorrhage and Hematoma in a Traumatic Brain Injury Mouse Model.
Front Neurol
; 12: 717513, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34650505
12.
PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease.
Sci Transl Med
; 13(604)2021 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-34321320
13.
Lysophosphatidylcholine activates adipocyte glucose uptake and lowers blood glucose levels in murine models of diabetes.
J Biol Chem
; 284(49): 33833-40, 2009 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-19815546
14.
Pathological Functions of LRRK2 in Parkinson's Disease.
Cells
; 9(12)2020 11 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33266247
15.
High-Performance Conducting Polymer Nanotube-based Liquid-Ion Gated Field-Effect Transistor Aptasensor for Dopamine Exocytosis.
Sci Rep
; 10(1): 3772, 2020 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32111933
16.
LRRK2 and membrane trafficking: nexus of Parkinson's disease.
BMB Rep
; 52(9): 533-539, 2019 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-31383252
17.
Improved dynamic monitoring of transcriptional activity during longitudinal analysis in the mouse brain.
Biol Open
; 8(1)2019 Jan 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30341106
18.
Characterization of Parkinson's disease-related pathogenic TMEM230 mutants.
Anim Cells Syst (Seoul)
; 22(2): 140-147, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30460091
19.
Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage.
Cell Death Dis
; 9(11): 1125, 2018 11 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30420654
20.
Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration.
Mol Neurodegener
; 13(1): 8, 2018 02 13.
Artigo
Inglês
| MEDLINE | ID: mdl-29439717