Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 210
Filtrar
1.
Am J Emerg Med ; 76: 217-224, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38128162

RESUMO

BACKGROUND: The COVID-19 pandemic has posed significant challenges to healthcare systems worldwide, including an increase in out-of-hospital cardiac arrests (OHCA). Healthcare providers are now required to use personal protective equipment (PPE) during cardiopulmonary resuscitation (CPR). Additionally, mechanical CPR devices have been introduced to reduce the number of personnel required for resuscitation. This study aimed to compare the outcomes of CPR performed with a mechanical device and the outcomes of manual CPR performed by personnel wearing PPE. METHODS: This multicenter observational study utilized data from the Korean Cardiac Arrest Research Consortium registry. The study population consisted of OHCA patients who underwent CPR in emergency departments (EDs) between March 2020 and June 2021. Patients were divided into two equal propensity score matched groups: mechanical CPR group (n = 421) and PPE-equipped manual CPR group (n = 421). Primary outcomes included survival rates and favorable neurological outcomes at discharge. Total CPR duration in the ED was also assessed. RESULTS: There were no significant between-group differences with respect to survival rate at discharge (mechanical CPR: 7.4% vs PPE-equipped manual CPR: 8.3%) or favorable neurological outcomes (3.3% vs. 3.8%, respectively). However, the mechanical CPR group had a longer duration of CPR in the ED compared to the manual CPR group. CONCLUSION: This study found no significant differences in survival rates and neurological outcomes between mechanical CPR and PPE-equipped manual CPR in the ED setting. However, a longer total CPR duration was observed in the mechanical CPR group. Further research is required to explore the impact of PPE on healthcare providers' performance and fatigue during CPR in the context of the pandemic and beyond.


Assuntos
COVID-19 , Reanimação Cardiopulmonar , Serviços Médicos de Emergência , Parada Cardíaca Extra-Hospitalar , Humanos , Reanimação Cardiopulmonar/métodos , Pandemias , COVID-19/epidemiologia , Parada Cardíaca Extra-Hospitalar/terapia
2.
Int J Qual Health Care ; 36(2)2024 Jun 22.
Artigo em Inglês | MEDLINE | ID: mdl-38907579

RESUMO

Near Real-Time Feedback (NRTF) on the patient's experience with care, coupled with data relay to providers, can inform quality-of-care improvements, including at the point of care. The objective is to systematically review contemporary literature on the impact of the use of NRTF and data relay to providers on standardized patient experience measures. Six scientific databases and five specialty journals were searched supplemented by snowballing search strategies, according to the registered study protocol. Eligibility included studies in English (2015-2023) assessing the impact of NRTF and data relay on standardized patient-reported experience measures as a primary outcome. Eligibility and quality appraisals were performed by two independent reviewers. An expert former patient (Patient and Family Advisory Council and communication sciences background) helped interpret the results. Eight papers met review eligibility criteria, including three randomized controlled trials (RCTs) and one non-randomized study. Three of these studies involved in-person NRTF prior to data relay (patient-level data for immediate corrective action or aggregated and peer-compared) and led to significantly better results in all or some of the experience measures. In turn, a kiosk-based NRTF achieved no better experience results. The remaining studies were pre-post designs with mixed or neutral results and greater risks of bias. In-person NRTF on the patient experience followed by rapid data relay to their providers, either patient-level or provider-level as peer-compared, can improve the patient experience of care. Reviewed kiosk-based or self-reported approaches combined with data relay were not effective. Further research should determine which approach (e.g. who conducts the in-person NRTF) will provide better, more efficient improvements and under which circumstances.


Assuntos
Retroalimentação , Satisfação do Paciente , Humanos , Melhoria de Qualidade , Qualidade da Assistência à Saúde
3.
Pediatr Emerg Care ; 2024 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-38713833

RESUMO

OBJECTIVE: This study aimed to identify predictive biomarkers for unscheduled emergency department (ED) revisits within 24 hours of discharge in infants diagnosed with acute bronchiolitis (AB). METHODS: A retrospective observational study was conducted on infants diagnosed with AB who visited 3 emergency medical centers between January 2020 and December 2022. The study excluded infants with comorbidities, congenital diseases, and prematurity and infants who revisited the ED after 24 hours of discharge. Demographic data, vital signs, and laboratory results were collected from the medical records. Univariable and multivariable logistic regression analyses were performed on factors with P of less than 0.1 in univariable analysis. Receiver operator curve analysis was used to assess the accuracy of lactate measurements in predicting ED revisits within 24 hours of discharge. RESULTS: Out of 172 participants, 100 were in the revisit group and 72 in the discharge group. The revisit group was significantly younger and exhibited higher lactate levels, lower pH values, and higher pCO2 levels compared to the discharge group. Univariable logistic regression identified several factors associated with revisits. Multivariable analysis found that only lactate was a variable correlated with predicting ED revisits (odds ratio, 18.020; 95% confidence interval [CI], 5.764-56.334). The receiver operator curve analysis showed an area under the curve of 0.856, with an optimal lactate cutoff value of 2.15. CONCLUSION: Lactate value in infants diagnosed with AB were identified as a potential indicator of predicting unscheduled ED revisits within 24 hours of discharge. The predictive potential of lactate levels holds promise for enhancing prognosis prediction, reducing health care costs, and alleviating ED overcrowding. However, given the study's limitations, a more comprehensive prospective investigation is recommended to validate these findings.

4.
J Cell Physiol ; 238(10): 2425-2439, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-37642258

RESUMO

Bone resorption can be caused by excessive differentiation and/or activation of bone-resorbing osteoclasts. While microbe-associated molecular patterns can influence the differentiation and activation of bone cells, little is known about the role of lipoteichoic acid (LTA), a major cell wall component of Gram-positive bacteria, in the regulation of bone metabolism. In this study, we investigated the effect of LTA on bone metabolism using wild-type Staphylococcus aureus and the LTA-deficient mutant strain. LTA-deficient S. aureus induced higher bone loss and osteoclast differentiation than wild-type S. aureus. LTA isolated from S. aureus (SaLTA) inhibited osteoclast differentiation from committed osteoclast precursors in the presence of various osteoclastogenic factors by downregulating the expression of NFATc1. Remarkably, SaLTA attenuated the osteoclast differentiation from committed osteoclast precursors of TLR2-/- or MyD88-/- mice and from the committed osteoclast precursors transfected with paired immunoglobulin-like receptor B-targeting siRNA. SaLTA directly interacted with gelsolin, interrupting the gelsolin-actin dissociation which is a critical process for osteoclastogenesis. Moreover, SaLTA suppressed the mRNA expression of dendritic cell-specific transmembrane protein, ATPase H+ transporting V0 subunit D2, and Integrin, which encode proteins involved in cell-cell fusion of osteoclasts. Notably, LTAs purified from probiotics, including Bacillus subtilis, Enterococcus faecalis, and Lactobacillus species, also suppressed Pam2CSK4- or RANKL-induced osteoclast differentiation. Taken together, these results suggest that LTAs have anti-resorptive activity through the inhibition of osteoclastogenesis by interfering with the gelsolin-actin dissociation and may be used as effective therapeutic agents for the prevention or treatment of inflammatory bone diseases.

5.
Environ Res ; 216(Pt 1): 114440, 2023 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-36208782

RESUMO

BACKGROUND: Numerous studies have suggested that long-term exposure to particulate matter ≤2.5 µm (PM2.5) may cause cardiovascular morbidity and mortality. However, susceptibility among those with a history of ischemic heart disease is less clearly understood. We aimed to evaluate whether long-term PM2.5 exposure is related to mortality among patients with ischemic heart disease. METHODS: We followed up 306,418 patients hospitalized with ischemic heart disease in seven major cities in South Korea between 2008 and 2016 using the National Health Insurance Database. We linked the modeled PM2.5 data corresponding to each patient's administrative districts and estimated hazard ratios (HRs) of cause-specific mortality associated with the long-term exposure to PM2.5 in time-varying Cox proportional hazard models after adjusting for individual- and area-level characteristics. We also estimated HRs by sex, age group (65-74 vs. ≥75 years), and household income. RESULTS: Of the patients with ischemic heart disease, mean age at the discharge was 76.8 years, and 105,913 died during a mean follow-up duration of 21.4 months. The HR of all-cause mortality was 1.10 [95% confidence intervals (CI): 1.07, 1.14] per 10 µg/m3 increase in a 12-month moving average PM2.5. The HRs of cardiovascular, stroke, and ischemic heart disease were 1.17 (95% CI: 1.11, 1.24), 1.17 (95% CI: 1.06, 1.30), and 1.25 (95% CI: 1.15, 1.35), respectively. The subgroup analyses showed that participants aged 65-74 years were more susceptible to adverse effects of PM2.5 exposure. We did not observe any differences in the risk by sex and household income. CONCLUSION: Mortality from all-cause and cardiovascular disease following hospitalization due to ischemic heart disease was higher among individuals with greater PM2.5 exposure in seven major cities in South Korea. The result supports the association of long-term exposure to air pollution with poor prognosis among patients with ischemic heart disease.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Doenças Cardiovasculares , Infarto do Miocárdio , Isquemia Miocárdica , Humanos , Poluentes Atmosféricos/toxicidade , Poluentes Atmosféricos/análise , Exposição Ambiental/efeitos adversos , Exposição Ambiental/análise , Estudos de Coortes , Poluição do Ar/efeitos adversos , Poluição do Ar/análise , Material Particulado/análise , Isquemia Miocárdica/epidemiologia , Infarto do Miocárdio/induzido quimicamente
6.
Int Arch Occup Environ Health ; 96(2): 191-200, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-36008500

RESUMO

PURPOSE: The relationship between night-shift work and obstructive sleep apnea (OSA) is well known, but that between OSA and long working hours is still unknown. This study explores the association between long working hours and OSA. METHODS: Using cross-sectional Korean National Health and Nutrition Examination Survey 2020 data, we made multiple logistic regression models to calculate odds ratios (ORs) between weekly working hours and STOP-BANG scores for OSA screening. Stratified regression models by night or rotating shift work were also made. RESULTS: In an adjusted model of STOP-BANG high-risk versus low-risk groups, the OR in the group exceeding 40 h/wk was higher but not statistically significant, 1.19 [95% confidence interval (CI) 0.66-2.15] compared to the group working 40 h/wk (standard working hours) or less. In the group exceeding 52 h/wk, the OR was 2.03 with statistical significance (95% CI 1.08-3.80). In the stratification analysis of daytime and night-shift work, the daytime worker results were similar to those in the non-stratified model. The point estimation values of ORs in the night-shift workers were higher than in the daytime workers; however, we did not observe a statistical significance. CONCLUSION: Long working hours can increase the risk of OSA assessed by STOP-BANG scores.


Assuntos
Apneia Obstrutiva do Sono , Humanos , Estudos Transversais , Inquéritos e Questionários , Inquéritos Nutricionais , Polissonografia/métodos
7.
BMC Public Health ; 23(1): 1473, 2023 08 02.
Artigo em Inglês | MEDLINE | ID: mdl-37533044

RESUMO

BACKGROUND: We aimed to examine the lymphohematopoietic cancer mortality in a cohort of workers at a semiconductor manufacturing company in South Korea according to their jobs. METHODS: A retrospective cohort was constructed using the personnel records of semiconductor manufacturing workers who were employed in a semiconductor company in South Korea in 1998-2012. Data on their vital status and causes of death were obtained from the National Statistical Office of South Korea. The standardized mortality ratios (SMRs) of lymphohematopoietic cancer were calculated. RESULTS: A total of 288 deaths were reported, of which 22 were caused by lymphohematopoietic cancer, among 65,782 workers in 878,325 person-years. The SMRs for lymphohematopoietic cancer were 0.78 (95% confidence interval [CI] = 0.39-1.40; the number of observed cases [Obs] = 11) among male workers and 1.71 (95% CI = 0.85-3.06; Obs = 11) among female workers. Among female operators, excess deaths due to lymphohematopoietic cancer (SMR = 2.59, 95% CI = 1.24-4.76) and leukemia (SMR = 2.92, 95% CI = 1.26-5.76) were observed. However, they were not observed among office workers, facility managers, utility managers, or process managers. CONCLUSION: Female operators involved in the semiconductor wafer fabrication process had higher risk of mortality from lymphohematopoietic cancer.


Assuntos
Leucemia Mieloide Aguda , Neoplasias , Doenças Profissionais , Exposição Ocupacional , Humanos , Masculino , Feminino , Estudos Retrospectivos , Exposição Ocupacional/efeitos adversos , Estudos de Coortes , Causas de Morte , Semicondutores
8.
BMC Public Health ; 23(1): 549, 2023 03 23.
Artigo em Inglês | MEDLINE | ID: mdl-36959592

RESUMO

BACKGROUND: Telecommuting has expanded greatly during the COVID-19 pandemic. Since the advent of remote working from home, there has been an ongoing controversy about the positive or negative health-related impact of telecommuting. This study aimed to investigate change in the occupational health risk in South Korean workers involved in telecommuting during the pandemic period compared to daily commuters. METHODS: A population-based cross-sectional study of South Korean workers using the secondary data from the 6th Korean Working Conditions Survey (2020-2021) was designed. A total of 12,354 white-collar wage employees were selected as the study sample. Telecommuting, depression, anxiety, insomnia, fatigue, musculoskeletal pain, headache-eye strain, absenteeism, and presenteeism were measured by self-reported data. Multiple logistic regression models, including gender stratification analysis, were used to estimate the adjusted odds ratio (AOR) with a 95% confidence interval (CI) for the health outcomes of telecommuters. RESULTS: Among the study population, 338 males and 318 females were reported to be telecommuters. The entirely adjusted regression model showed a positive association between telecommuting and anxiety (AOR = 2.82; 95% CI, 1.93-4.10), insomnia (AOR = 1.93; 95% CI, 1.27-2.92), fatigue (AOR = 1.76; 95% CI, 1.30-2.37), musculoskeletal pain (AOR = 1,76; 95% CI, 1.33-2.32), headache-eye strain (AOR = 1.94; 95% CI, 1.48-2.54), presenteeism (AOR = 1.66; 95% CI, 1.20-2.28) respectively. Gender difference was identified in that only female telecommuters had a higher risk of depression (AOR = 1.62; 95% CI, 1.04-2.53) and insomnia (AOR = 2.07; 95% CI, 1.26-3.41) than daily commuters in the adjusted model. CONCLUSION: Telecommuting was significantly associated with an increased risk of various health problems among South Korean workers and females were identified as a more vulnerable group. Although further research is required to ascertain the causal relationship, public health intervention should be considered to prevent the negative effects of telecommuting.


Assuntos
COVID-19 , Dor Musculoesquelética , Distúrbios do Início e da Manutenção do Sono , Masculino , Humanos , Feminino , COVID-19/epidemiologia , Teletrabalho , Pandemias , Estudos Transversais , Dor Musculoesquelética/epidemiologia , Distúrbios do Início e da Manutenção do Sono/epidemiologia , República da Coreia/epidemiologia , Cefaleia/epidemiologia , Fadiga/epidemiologia , Avaliação de Resultados em Cuidados de Saúde
9.
Ecotoxicol Environ Saf ; 268: 115677, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37979362

RESUMO

BACKGROUND: Noise is defined as unwanted sound. It may induce negative emotions and mental health problems and may even lead to increased suicide risk. However, the impact of noise exposure on environmental diseases and disease severity is not well understood. This study aimed to elucidate the association between night-time noise exposure and the prevalence of environmental diseases in South Korea. METHODS: We conducted an analysis of the Environmental Disease Database provide by the National Health Insurance Service (NHIS) from 2013 to 2017. After spatially interpolating the noise data provided by the National Noise Information System (NNIS), night-time noise values in the district level were obtained by calculating the mean noise values at the administrative district level. The linear regression analyses were performed to test the association between the age-standardized prevalence ratio (SPR) and the night-time noise exposure in the district level. RESULTS: In areas with high night-time noise exposure (≥55 dB), the SPR for atopic dermatitis and allergic rhinitis were 1.0515 (95 % confidence interval [CI]:1.0508-1.0521) and 1.0202 (95 % CI:1.0201-1.0204), respectively, which were higher than those in the general population. The SPR for environmental diseases, including atopic dermatitis, asthma, and allergic rhinitis, was 1.0104 (95 % CI:1.0103-1.0105). Additionally, a significant linear association was observed between the level of nocturnal noise exposure and the total hospitalization period for atopic dermatitis (ß = 399.3, p < 0.01). CONCLUSION: We provide evidence of a significant association between night-time environmental noise and environmental diseases, particularly atopic dermatitis and allergic rhinitis. Furthermore, we observed a significant linear association between night-time noise exposure and the severity of atopic dermatitis.


Assuntos
Asma , Dermatite Atópica , Rinite Alérgica , Humanos , Dermatite Atópica/epidemiologia , Dermatite Atópica/etiologia , Fatores de Risco , Asma/epidemiologia , Asma/etiologia , Rinite Alérgica/epidemiologia , Rinite Alérgica/etiologia , Suscetibilidade a Doenças
10.
Nano Lett ; 22(14): 5742-5750, 2022 Jul 27.
Artigo em Inglês | MEDLINE | ID: mdl-35666985

RESUMO

This paper reports an approach to repurpose low-cost, bulk multilayer MoS2 for development of ultraefficient hydrogen evolution reaction (HER) catalysts over large areas (>cm2). We create working electrodes for use in HER by dry transfer of MoS2 nano- and microflakes to gold thin films deposited on prestrained thermoplastic substrates. By relieving the prestrain at a macroscopic scale, a tunable level of tensile strain is developed in the MoS2 and consequently results in a local phase transition as a result of spontaneously formed surface wrinkles. Using electrochemical impedance spectroscopy, we verified that electrochemical activation of the strained MoS2 lowered the charge transfer resistance within the materials system, achieving HER activity comparable to platinum (Pt). Raman and X-ray photoelectron spectroscopy show that desulfurization in the multilayer MoS2 was promoted by the phase transition; the combined effect of desulfurization and the lower charge resistance induced superior HER performance.

11.
Occup Environ Med ; 79(4): 277-286, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-33910983

RESUMO

OBJECTIVES: There has been no research on sedentary behaviour in the occupational domain that occupies a large portion of the daily life. METHODS: We conducted a meta-analysis to investigate the association between sedentary work and colorectal cancer. We searched PubMed, Embase and Cochrane databases up to 12 August 2020 for peer-reviewed journal articles that assessed the association between sedentary work and colon or rectal cancer. Pooled estimates of ORs were obtained using random effects models. Statistical tests for publication bias, heterogeneity and sensitivity analysis were applied. RESULTS: Of the 5 381 studies initially identified, 23 studies with 64 reports were eligible for inclusion. Sedentary work significantly increased the risk of colon cancer (pooled OR=1.21, 95% CI 1.11 to 1.31, p value ≤0.0001) and rectal cancer (pooled OR=1.08, 95% CI 1.00 to 1.16, p value=0.0395). The adjustment for leisure time physical activity attenuated the association and made the risk estimates non-significant for sedentary behaviour, but the association was independent of sex, control of body mass index and assessment of sedentary behaviour. CONCLUSIONS: We found evidence of association between sedentary work and the risk of colon or rectal cancer. Limiting excessive sedentary work could be an important means of preventing colon and rectal cancer.


Assuntos
Neoplasias do Colo , Neoplasias Retais , Índice de Massa Corporal , Neoplasias do Colo/epidemiologia , Neoplasias do Colo/etiologia , Humanos , Neoplasias Retais/epidemiologia , Neoplasias Retais/etiologia , Comportamento Sedentário
12.
Sensors (Basel) ; 22(11)2022 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-35684673

RESUMO

Although the LiDAR sensor provides high-resolution point cloud data, its performance degrades when exposed to dust environments, which may cause a failure in perception for robotics applications. To address this issue, our study designed an intensity-based filter that can remove dust particles from LiDAR data in two steps. In the first step, it identifies potential points that are likely to be dust by using intensity information. The second step involves analyzing the point density around selected points and removing them if they do not meet the threshold criterion. To test the proposed filter, we collected experimental data sets under the existence of dust and manually labeled them. Using these data, the de-dusting performance of the designed filter was evaluated and compared to several types of conventional filters. The proposed filter outperforms the conventional ones in achieving the best performance with the highest F1 score and removing dust without sacrificing the original surrounding data.

13.
Occup Environ Med ; 78(2): 86-91, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-32912859

RESUMO

OBJECTIVE: This study aims to explore the association between physical activity and high-sensitivity C reactive protein, based on different types of physical activity-occupational and leisure time. METHODS: Using cross-sectional data from the Korea National Health and Nutrition Examination Survey 2015-2018, we explored the association between different types of self-reported physical activity and high levels of high-sensitivity C reactive protein (>3 mg/L). We estimated the ORs for high-level high-sensitivity C reactive protein using multiple logistic regression models after adjusting for covariates from 12 970 eligible subjects (mean age 44.8). RESULTS: Compared with subjects who did not engage in moderate-to-vigorous level of occupational physical activity (OPA), the group that engaged in moderate-to-vigorous level of OPA showed a significantly high OR (1.32, 95% CI (1.03 to 1.69)), whereas the group that engaged in moderate-to-vigorous level of leisure-time physical activity (LPA) yielded a low OR (0.84, 95% CI (0.69 to 1.01)). The group that engaged in moderate-to-vigorous level of OPA but not LPA showed a significantly high OR (1.76, 95% CI (1.27 to 2.45)) compared with subjects who engaged in moderate-to-vigorous level of LPA but not in OPA. CONCLUSIONS: OPA is directly associated with high C reactive protein levels, suggesting that it increases the risk of inflammation.


Assuntos
Proteína C-Reativa/metabolismo , Exercício Físico , Ocupações , Adulto , Estudos Transversais , Feminino , Humanos , Atividades de Lazer , Masculino , Saúde Ocupacional , República da Coreia
14.
Environ Res ; 197: 111013, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33716025

RESUMO

BACKGROUND: Particulate matter (PM) less than 2.5 µm in diameter and 10 µm (PM10) contains heavy metals, but whether exposure to PM is significantly associated with the burden of heavy metal exposure in the population is unknown. We investigated the association between exposure to PM and blood concentrations of lead (Pb), cadmium (Cd), and mercury (Hg) in Korean housewives. MATERIALS & METHODS: From July 2017 to January 2020, we recruited 115 housewives in Ulsan, Republic of Korea. After excluding participants with missing information, we finally included 88 Korean housewives in our study. We measured the concentrations of indoor PM using a gravimetric method 24 h before blood sampling and the concentrations of Cd, Pb, and Hg in blood, twice at a 1-year interval. We used a linear mixed effect model to estimate the associations between indoor PM and blood heavy metals. RESULTS: Exposure to PM10 was significantly associated with blood concentrations of Cd among Korean housewives. A 10 µg/m3 increase of PM10 the previous day was associated with a 2.8% (95% confidence interval (CI) = 1.1%, 4.6%) and a 1.5% (95% CI = -0.1%, 3.1%) increase in blood concentrations of Cd and Pb in the linear mixed effect model, respectively. CONCLUSION: There was a significant association between indoor PM exposure and blood Cd concentrations among Korean housewives. This result suggests that the body burden of heavy metals is significantly associated with air pollution.


Assuntos
Poluentes Atmosféricos , Metais Pesados , Poluentes Atmosféricos/análise , Monitoramento Ambiental , Humanos , Metais Pesados/análise , Material Particulado/análise , República da Coreia
15.
Environ Res ; 197: 111139, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33848554

RESUMO

Although many studies have evaluated the effects of ambient particulate matter with diameters of less than 2.5 µm (PM2.5) on stroke mortality in the general population, little is known about the mortality effects of PM2.5 in post-stroke populations. Therefore, a retrospective cohort was constructed using information from the health insurance database to evaluate whether exposure to PM2.5 is associated with increased mortality in aged stroke survivors residing in seven Korean metropolitan cities. A total of 45,513 older adults (≥65 years) who visited emergency rooms due to stroke and who were discharged alive between 2008 and 2016 were followed up. By using district-level modeled PM2.5 concentrations and a time-varying Cox proportional hazard model, associations between 1-month and 2-month moving average PM2.5 exposures and mortality in stroke survivors were evaluated. The annual average concentration of PM2.5 was 27.9 µg/m3 in the seven metropolitan cities, and 14,880 subjects died during the follow-up period. A 10 µg/m3 increase in the 1-month and 2-month moving average PM2.5 exposures was associated with mortality hazard ratios of 1.07 (95% confidence interval: 1.05, 1.09) and 1.06 (95% confidence interval: 1.03, 1.08), respectively. The effects of PM2.5 were similar across types of stroke (ischemic and hemorrhagic), age groups (65-74, 75-84, and ≥85), and income groups (low and high) but were greater in women than in men. This study highlights the adverse health effects of ambient PM2.5 in post-stroke populations. Active avoidance behaviors against PM2.5 are recommended for aged stroke survivors.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Acidente Vascular Cerebral , Idoso , Poluentes Atmosféricos/análise , Poluição do Ar/efeitos adversos , Poluição do Ar/análise , Cidades , Estudos de Coortes , Exposição Ambiental/efeitos adversos , Exposição Ambiental/análise , Feminino , Humanos , Masculino , Material Particulado/análise , República da Coreia/epidemiologia , Estudos Retrospectivos
16.
Int Arch Occup Environ Health ; 94(7): 1605-1615, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34089350

RESUMO

PURPOSE: We aimed to investigate the association between air pollution concentration levels and hospital admissions for heart failure (HF) among older adults in metropolitan cities in South Korea. METHODS: We used hospital admission data of 1.8 million older adults in seven metropolitan cities from 2008 to 2016, derived from the National Health Insurance Service of South Korea. Daily HF admission data were linked to air pollutants concentrations for the respective dates, including particulate matter less than 2.5 µm in size (PM2.5), 10 µm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone. We estimated the association between air pollutants and daily HF admissions using quasi-Poisson generalized additive models for each city. RESULTS: During the study period, 142,490 hospital admissions for HF were noted. Increases of 10 µg/m3 of PM2.5 and PM10, and 10 ppb of SO2, NO2, and CO were associated with an increased risk of HF admission by 0.93% ([95% confidence intervals 0.51-1.36], 0.55% [0.31-0.80], 6.04% [2.15-10.08], 1.10% [0.38-1.82], and 0.05% [0.01-0.09]), respectively, on the same day. Increases in mean exposure to PM2.5, PM10, and SO2 for 8 days from the concurrent day were also significantly associated with HF admissions. During the warm season, the risk of HF admissions increased shortly after an increase in PM2.5, whereas prolonged effects were observed during the cold season. CONCLUSION: Our study suggests the adverse effects of air pollution on HF. Moreover, the evidence of seasonality may help tailor protection guidelines for older adults.


Assuntos
Poluição do Ar/análise , Exposição Ambiental , Insuficiência Cardíaca/epidemiologia , Hospitalização/estatística & dados numéricos , Poluentes Atmosféricos/análise , Monóxido de Carbono/análise , Cidades/epidemiologia , Humanos , Dióxido de Nitrogênio/análise , Ozônio/análise , Material Particulado/análise , República da Coreia/epidemiologia , Estações do Ano , Dióxido de Enxofre/análise
17.
Orthod Craniofac Res ; 24 Suppl 1: 92-102, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33277824

RESUMO

OBJECTIVE: To systematically review the effects of cortical bone thickness (CBT) and bone mass density (BMD) on miniscrew success rates. METHODS: MEDLINE, the Cochrane Library and Scopus were searched up to June 2020. Of a total of 5734 articles, seven studies were finally selected for the review. RESULTS: The overall mean success rate weighted by the number of miniscrews was 87.21% (89.87% in the maxilla and 79.24% in the mandible). There was a significantly higher success rate for miniscrews placed in the maxilla compared with those in the mandible (P < .05). CBT showed small positive effect on the success rate of the miniscrews although it failed to reach a statistical significance. The cortical BMD had a minimal effect on the success of the miniscrews. The cancellous BMD demonstrated a very strong effect on the success of the miniscrews in the maxilla, whereas it showed a moderately negative effect in the mandible. LIMITATIONS: Because of the small number and clinical heterogeneity of the included studies, the results should be interpreted with caution. Further randomized clinical studies with a large sample size are recommended.


Assuntos
Procedimentos de Ancoragem Ortodôntica , Densidade Óssea , Parafusos Ósseos , Osso Cortical/diagnóstico por imagem , Mandíbula/diagnóstico por imagem , Maxila/diagnóstico por imagem
18.
Sensors (Basel) ; 21(7)2021 Mar 24.
Artigo em Inglês | MEDLINE | ID: mdl-33804898

RESUMO

An around view monitoring (AVM) system acquires the front, rear, left, and right-side information of a vehicle using four cameras and transforms the four images into one image coordinate system to monitor around the vehicle with one image. Conventional AVM calibration utilizes the maximum likelihood estimation (MLE) to determine the parameters that can transform the captured four images into one AVM image. The MLE requires reference data of the image coordinate system and the world coordinate system to estimate these parameters. In conventional AVM calibration, many aligned calibration boards are placed around the vehicle and are measured to extract the reference sample data. However, accurately placing and measuring the calibration boards around a vehicle is an exhaustive procedure. To remediate this problem, we propose a novel AVM calibration method that requires only four randomly placed calibration boards by estimating the location of each calibration board. First, we define the AVM errors and determine the parameters that minimize the error in estimating the location. We then evaluate the accuracy of the proposed method through experiments using a real-sized vehicle and an electric vehicle for children to show that the proposed method can generate an AVM image similar to the conventional AVM calibration method regardless of a vehicle's size.

19.
Sensors (Basel) ; 21(9)2021 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-34067009

RESUMO

Vehicles today have many advanced driver assistance control systems that improve vehicle safety and comfort. With the development of more sophisticated vehicle electronic control and autonomous driving technology, the need and effort to estimate road surface conditions is increasing. In this paper, a real-time road surface classification algorithm, based on a deep neural network, is developed using a database collected through an intelligent tire sensor system with a three-axis accelerometer installed inside the tire. Two representative types of network, fully connected neural network (FCNN) and convolutional neural network (CNN), are learned with each of the three-axis acceleration sensor signals, and their performances were compared to obtain an optimal learning network result. The learning results show that the road surface type can be classified in real-time with sufficient accuracy when the longitudinal and vertical axis acceleration signals are trained with the CNN. In order to improve classification accuracy, a CNN with multiple input that can simultaneously learn 2-axis or 3-axis acceleration signals is suggested. In addition, by analyzing how the accuracy of the network is affected by number of classes and length of input data, which is related to delay of classification, the appropriate network can be selected according to the application. The proposed real-time road surface classification algorithm is expected to be utilized with various vehicle electronic control systems and makes a contribution to improving vehicle performance.

20.
Am J Orthod Dentofacial Orthop ; 159(4): 502-511, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33495061

RESUMO

INTRODUCTION: The objectives of this study were to evaluate the effects of bicortical engagement by microimplants with maxillary skeletal expanders on pterygopalatine sutures opening and to analyze the postexpansion skeletal changes associated with it. METHODS: Eighteen subjects treated with maxillary skeletal expanders were examined for pterygopalatine suture openings. Eight subjects who showed no evidence of the suture opening were assigned to the nonsplit group (NG), whereas 10 subjects with opened sutures were assigned to the split group (SG). Preexpansion and postexpansion cone-beam computed tomography images were superimposed for each group, and the changes in the 2 groups were compared. Finally, cone-beam computed tomography volumes were reoriented along the axis of each microimplant to check the bicortical engagement of the 4 microimplants. RESULTS: There was a significant correlation between the bicortical engagement of the orthodontic microimplants and the pterygopalatine suture opening (P = 0.0003). In the NG, the average amount of transverse expansion measured at the center of resistance of the maxillary first molars, anterior nasal spine, and posterior nasal spine (PNS) was 4.33 mm, 2.22 mm, and 1.58 mm, respectively, whereas the transverse expansion in the SG was 5.29 mm, 2.21 mm, and 2.46 mm, respectively. The magnitude of transverse expansion at PNS was significantly higher in the SG than in the NG (P = 0.036). The PNS also showed a significant anterior displacement in the SG (0.89 mm) compared with the NG (0.06 mm) (P = 0.033). CONCLUSIONS: Bicortical microimplant anchorage is essential for pterygopalatine suture opening in microimplant-assisted maxillary skeletal expansion, which may result in further skeletal expansion and forward movement in the posterior part of the palatomaxillary complex.


Assuntos
Maxila , Técnica de Expansão Palatina , Tomografia Computadorizada de Feixe Cônico , Humanos , Maxila/diagnóstico por imagem , Maxila/cirurgia , Dente Molar , Suturas
SELEÇÃO DE REFERÊNCIAS
Detalhe da pesquisa