An Enantioselective e-Nose: An Array of Nanoporous Homochiral MOF Films for Stereospecific Sensing of Chiral Odors.

Chirality is essential in nature and often pivotal for biological information transfer, for example, via odor messenger molecules. While the human nose can distinguish the enantiomers of many chiral odors, the technical realization by an artificial sensor or an electronic nose, e-nose, remains a challenge. Herein, we present an array of six sensors coated with nanoporous metal-organic framework (MOF) films of different homochiral and achiral structures, working as an enantioselective e-nose. While the achiral-MOF-film sensors show identical responses for both isomers of one chiral odor molecule, the responses of the homochiral MOF films differ for different enantiomers. By machine learning algorithms, the combined array data allow the stereoselective identification of all compounds, here tested for five pairs of chiral odor molecules. We foresee the chiral-MOF-e-nose, able to enantioselectively detect and discriminate chiral odors, to be a powerful approach towards advanced odor sensing.

Nanostructured front electrodes for perovskite/c-Si tandem photovoltaics.

The rise in the power conversion efficiency (PCE) of perovskite solar cells has triggered enormous interest in perovskite-based tandem photovoltaics. One key challenge is to achieve high transmission of low energy photons into the bottom cell. Here, nanostructured front electrodes for 4-terminal perovskite/crystalline-silicon (perovskite/c-Si) tandem solar cells are developed by conformal deposition of indium tin oxide (ITO) on self-assembled polystyrene nanopillars. The nanostructured ITO is optimized for reduced reflection and increased transmission with a tradeoff in increased sheet resistance. In the optimum case, the nanostructured ITO electrodes enhance the transmittance by ∼7% (relative) compared to planar references. Perovskite/c-Si tandem devices with nanostructured ITO exhibit enhanced short-circuit current density (2.9 mA/cm2 absolute) and PCE (1.7% absolute) in the bottom c-Si solar cell compared to the reference. The improved light in-coupling is more pronounced for elevated angle of incidence. Energy yield enhancement up to ∼10% (relative) is achieved for perovskite/c-Si tandem architecture with the nanostructured ITO electrodes. It is also shown that these nanostructured ITO electrodes are also compatible with various other perovskite-based tandem architectures and bear the potential to improve the PCE up to 27.0%.

Single-molecule spectroscopy on a ladder-type conjugated polymer: electron-phonon coupling and spectral diffusion.

We employ low-temperature single-molecule spectroscopy combined with pattern recognition techniques for data analysis on a methyl-substituted ladder-type poly(para-phenylene) (MeLPPP) to investigate the electron-phonon coupling to low-energy vibrational modes as well as the origin of the strong spectral diffusion processes observed for this conjugated polymer. The results indicate weak electron-phonon coupling to low-frequency vibrations of the surrounding matrix of the chromophores, and that low-energy intrachain vibrations of the conjugated backbone do not couple to the electronic transitions of MeLPPP at low temperatures. Furthermore, these findings suggest that the main line-broadening mechanism of the zero-phonon lines of MeLPPP is fast, unresolved spectral diffusion, which arises from conformational fluctuations of the side groups attached to the MeLPPP backbone as well as of the surrounding host material.

Visualization of astaxanthin localization in HT29 human colon adenocarcinoma cells by combined confocal resonance Raman and fluorescence microspectroscopy.

Astaxanthin, a carotenoid found in plants and seafood, exhibits antiproliferative, antioxidant and anticarcinogenic properties. We show that astaxanthin delivered with tetrahydrofuran is effectively taken up by cultured colon adenocarcinoma cells and is localized mostly in the cytoplasm as detected by confocal resonance Raman and broad-band fluorescence microspectroscopy image analysis. Cells incubated with beta-carotene at the same concentration as astaxanthin (10 microM) showed about a 50-fold lower cellular amount of beta-carotene, as detected by HPLC. No detectable Raman signal of beta-carotene was found in cells, but a weak broad-band fluorescence signal of beta-carotene was observed. beta-Carotene, like astaxanthin, was localized mostly in the cytoplasm. The heterogeneity of astaxanthin and beta-carotene cellular distribution in cells of intestinal origin suggests that the possible defense against reactive molecules by carotenoids in these cells may also be heterogeneous.