Detalhe da pesquisa
1.
A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.
Nature
; 546(7658): 376-380, 2017 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28562588
2.
Safety, Pharmacokinetics, and Causal Prophylactic Efficacy of KAF156 in a Plasmodium falciparum Human Infection Study.
Clin Infect Dis
; 73(7): e2407-e2414, 2021 10 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32644127
3.
Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria.
N Engl J Med
; 375(12): 1152-60, 2016 09 22.
Artigo
Inglês
| MEDLINE | ID: mdl-27653565
4.
A phase 1 evaluation of the pharmacokinetic/pharmacodynamic interaction of the anti-malarial agents KAF156 and piperaquine.
Malar J
; 17(1): 7, 2018 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29304859
5.
Bioavailability of Lumefantrine Is Significantly Enhanced with a Novel Formulation Approach, an Outcome from a Randomized, Open-Label Pharmacokinetic Study in Healthy Volunteers.
Antimicrob Agents Chemother
; 61(9)2017 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28630183
6.
Spiroindolone KAE609 for falciparum and vivax malaria.
N Engl J Med
; 371(5): 403-10, 2014 Jul 31.
Artigo
Inglês
| MEDLINE | ID: mdl-25075833
7.
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers.
Antimicrob Agents Chemother
; 58(10): 6209-14, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25114127
8.
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel Imidazolopiperazine KAF156 to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers.
Antimicrob Agents Chemother
; 58(11): 6437-43, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25136017
9.
Cryptosporidiosis Drug Discovery: Opportunities and Challenges.
ACS Infect Dis
; 2(8): 530-7, 2016 08 12.
Artigo
Inglês
| MEDLINE | ID: mdl-27626293
10.
Improving influx constant and ratio estimation in FDOPA brain PET analysis for Parkinson's disease.
J Nucl Med
; 46(10): 1737-44, 2005 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16204725
11.
Basal lamina visualization using color image processing and pattern recognition.
Appl Immunohistochem Mol Morphol
; 13(3): 273-6, 2005 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-16082255
12.
Strategies for laboratory cost containment and for pathologist shortage: centralised pathology laboratories with microwave-stimulated histoprocessing and telepathology.
Pathology
; 37(1): 5-9, 2005 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-15875727
13.
Digital imaging in pathology: theoretical and practical considerations, and applications.
Pathology
; 36(3): 234-41, 2004 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15203727
14.
An automated diagnostic system for tubular carcinoma of the breast--an overview of approach and considerations.
Stud Health Technol Inform
; 97: 57-72, 2003.
Artigo
Inglês
| MEDLINE | ID: mdl-15537231
15.
Digital imaging applications in anatomic pathology.
Adv Anat Pathol
; 10(2): 88-95, 2003 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-12605090