Detalhe da pesquisa
1.
Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.
Blood
; 139(26): 3737-3751, 2022 06 30.
Artigo
Inglês
| MEDLINE | ID: mdl-35443029
2.
Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1.
Biochem J
; 476(21): 3211-3226, 2019 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31652307
3.
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Blood
; 129(6): 771-782, 2017 02 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27956387
4.
Identification of sphingosine kinase 1 as a therapeutic target in B-lineage acute lymphoblastic leukaemia.
Br J Haematol
; 184(3): 443-447, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29359799
5.
The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism.
Sci Rep
; 12(1): 454, 2022 01 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35013382
6.
Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia.
EMBO Mol Med
; 14(7): e15203, 2022 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35514210
7.
Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells.
Cell Rep
; 40(7): 111182, 2022 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35977494
8.
Non-genetic heterogeneity, altered cell fate and differentiation therapy.
EMBO Mol Med
; 13(3): e12670, 2021 03 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33555144
9.
Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models.
Blood Adv
; 4(20): 5062-5077, 2020 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33080008
10.
Targeting sphingolipid metabolism as an approach for combination therapies in haematological malignancies.
Cell Death Discov
; 4: 72, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30062053
11.
Author Correction: Targeting sphingolipid metabolism as an approach for combination therapies in haematological malignancies.
Cell Death Discov
; 7(1): 170, 2021 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34226526