Detalhe da pesquisa
1.
Novel histone deacetylase inhibitor CT-101 induces γ-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects.
Blood Cells Mol Dis
; 93: 102626, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34856533
2.
Benserazide racemate and enantiomers induce fetal globin gene expression in vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease.
Blood Cells Mol Dis
; 89: 102561, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33744514
3.
MIR29B mediates epigenetic mechanisms of HBG gene activation.
Br J Haematol
; 186(1): 91-100, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30891745
4.
Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and ß-YAC transgenic mice.
Blood Cells Mol Dis
; 79: 102345, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31351219
5.
Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain.
Haematologica
; 103(9): e384-e387, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29622657
6.
Personalized Immunotherapy of Patients: Defining by Single-cell RNA-seq with Artificial Intelligence.
Med Res Arch
; 11(8)2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37736242
7.
Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation.
BMC Genomics
; 13: 153, 2012 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-22537182
8.
NRF2 mediates γ-globin gene regulation and fetal hemoglobin induction in human erythroid progenitors.
Haematologica
; 102(8): e285-e288, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28473619
9.
Why do tumor-infiltrating lymphocytes have variable efficacy in the treatment of solid tumors?
Front Immunol
; 13: 973881, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36341370
10.
Machine-learning Modeling for Personalized Immunotherapy- An Evaluation Module.
Biomed J Sci Tech Res
; 47(2): 38211-38216, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-37817882
11.
Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice.
PLoS One
; 17(5): e0261799, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35639781
12.
Genomic expression analysis by single-cell mRNA differential display of quiescent CD8 T cells from tumour-infiltrating lymphocytes obtained from in vivo liver tumours.
Immunology
; 127(1): 83-90, 2009 May.
Artigo
Inglês
| MEDLINE | ID: mdl-18778280
13.
Regulation of sexual dimorphism: mutational and chemogenetic analysis of the doublesex DM domain.
Mol Cell Biol
; 26(2): 535-47, 2006 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-16382145
14.
Mechanisms of NRF2 activation to mediate fetal hemoglobin induction and protection against oxidative stress in sickle cell disease.
Exp Biol Med (Maywood)
; 244(2): 171-182, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30674214
15.
MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease.
Exp Hematol
; 70: 85-96.e5, 2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30412705
16.
Editorial: Epigenetics in cancer: mechanisms and drug development-volume II.
Front Genet
; 14: 1242960, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37476412
17.
SRY-directed DNA bending and human sex reversal: reassessment of a clinical mutation uncovers a global coupling between the HMG box and its tail.
J Mol Biol
; 360(2): 310-28, 2006 Jul 07.
Artigo
Inglês
| MEDLINE | ID: mdl-16762365
18.
Editorial: Epigenetics in Cancer: Mechanisms and Drug Development.
Front Genet
; 13: 831704, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35836578
19.
Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.
JCI Insight
; 2(20)2017 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29046485
20.
DNA alterations in human aberrant crypt foci and colon cancers by random primed polymerase chain reaction.
Cancer Res
; 63(19): 6166-9, 2003 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-14559798