Detalhe da pesquisa
1.
Discovery of 2,4-diarylaminopyrimidine derivatives bearing sulfonamide moiety as novel FAK inhibitors.
Bioorg Chem
; 144: 107134, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38237389
2.
Synthesis of novel sulfonamide derivatives containing pyridin-3-ylmethyl 4-(benzoyl)piperazine-1-carbodithioate moiety as potent PKM2 activators.
Bioorg Chem
; 108: 104653, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33517002
3.
A thienopyridine, CB-20, exerts diuretic activity by inhibiting urea transporters.
Acta Pharmacol Sin
; 41(1): 65-72, 2020 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-31213671
4.
Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism.
Neurochem Res
; 44(12): 2786-2795, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31691883
5.
Transition Metal-Free Intermolecular C(sp2)-H Direct Amination of Furanones via a Redox Pathway.
J Org Chem
; 84(3): 1310-1319, 2019 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30607949
6.
Anti-inflammatory effect and mechanism of the spirocyclopiperazinium salt compound LXM-15 in rats and mice.
Inflamm Res
; 67(4): 363-370, 2018 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-29302720
7.
Synthesis and biological evaluation of curcumin derivatives modified with α-amino boronic acid as proteasome inhibitors.
Bioorg Med Chem Lett
; 28(14): 2459-2464, 2018 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29886021
8.
Antinociception of the spirocyclopiperazinium salt compound LXM-15 via activating α7 nAChR and M4 mAChR and inhibiting CaMKIIα/cAMP/CREB/CGRP signalling pathway in mice.
Regul Toxicol Pharmacol
; 94: 108-114, 2018 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-29353067
9.
Synthesis and biological activity of peptide proline-boronic acids as proteasome inhibitors.
Bioorg Med Chem
; 25(15): 4031-4044, 2017 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28634039
10.
Regioselective Ir(III)-catalyzed C-H alkynylation directed by 7-azaindoles.
Org Biomol Chem
; 14(10): 2944-9, 2016 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26878600
11.
Pharmacokinetic-pharmacodynamic modeling of the antitumor effect of TM208 and EGFR-TKI resistance in human breast cancer xenograft mice.
Acta Pharmacol Sin
; 37(6): 825-33, 2016 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-27133303
12.
LRD-22, a novel dual dithiocarbamatic acid ester, inhibits Aurora-A kinase and induces apoptosis and cell cycle arrest in HepG2 cells.
Biochem Biophys Res Commun
; 458(1): 201-7, 2015 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-25645017
13.
Design, synthesis and biological evaluation of pyridazino[3,4,5-de]quinazolin-3(2H)-one as a new class of PARP-1 inhibitors.
Bioorg Med Chem Lett
; 25(11): 2340-4, 2015 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25899312
14.
Asymmetric Michael addition reactions of nitroalkanes to 2-furanones catalyzed by bifunctional thiourea catalysts.
Org Biomol Chem
; 13(19): 5363-6, 2015 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-25877691
15.
New pyridin-3-ylmethyl carbamodithioic esters activate pyruvate kinase M2 and potential anticancer lead compounds.
Bioorg Med Chem
; 23(15): 4815-4823, 2015 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26081759
16.
CovalentDock Cloud: a web server for automated covalent docking.
Nucleic Acids Res
; 41(Web Server issue): W329-32, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23677616
17.
Thienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters.
Am J Physiol Renal Physiol
; 307(12): F1363-72, 2014 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25298523
18.
Inhibition of EGFR autophosphorylation plays an important role in the anti-breast cancer efficacy of the dithiocarbamate derivative TM208.
Acta Pharmacol Sin
; 35(2): 239-47, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24374811
19.
A convenient four-component one-pot synthesis of 2-amino-1,3,4-thiadiazoles in water.
Mol Divers
; 18(4): 737-43, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24974242
20.
CovalentDock: automated covalent docking with parameterized covalent linkage energy estimation and molecular geometry constraints.
J Comput Chem
; 34(4): 326-36, 2013 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-23034731