Detalhe da pesquisa
1.
Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor.
J Org Chem
; 84(8): 4780-4795, 2019 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-30475616
2.
Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug substances.
Analyst
; 144(9): 2872-2880, 2019 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30830135
3.
Promotion of a Ti-Mediated Mannich Reaction by a Proton Source.
J Org Chem
; 81(2): 723-8, 2016 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26656787
4.
A Diastereoselective Method for the Construction of syn-2'-Deoxy-2'-fluoronucleosides.
Org Lett
; 24(27): 4860-4864, 2022 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35793545
5.
Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods.
Chem Sci
; 12(26): 9031-9036, 2021 Jul 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34276931
6.
Supercritical fluid chromatography-photodiode array detection-electrospray ionization mass spectrometry as a framework for impurity fate mapping in the development and manufacture of drug substances.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1080: 42-49, 2018 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-29477066
7.
A multifunctional catalyst that stereoselectively assembles prodrugs.
Science
; 356(6336): 426-430, 2017 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28450641
8.
Synthesis of the GPR40 Partial Agonist MK-8666 through a Kinetically Controlled Dynamic Enzymatic Ketone Reduction.
Org Lett
; 18(22): 5888-5891, 2016 11 18.
Artigo
Inglês
| MEDLINE | ID: mdl-27802043
9.
A regioselective approach to 5-substituted-3-amino-1,2,4-triazines.
Org Lett
; 5(13): 2271-4, 2003 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-12816426
10.
Practical and cost-effective manufacturing route for the synthesis of a ß-lactamase inhibitor.
Org Lett
; 16(1): 174-7, 2014 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-24329136
11.
A highly efficient asymmetric synthesis of vernakalant.
Org Lett
; 16(10): 2716-9, 2014 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-24786635
12.
Dynamic kinetic resolution: asymmetric transfer hydrogenation of alpha-alkyl-substituted beta-ketoamides.
Org Lett
; 12(3): 512-5, 2010 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-20028132
13.
Synthesis of a tertiary carbinamide via a novel Rh-catalyzed asymmetric hydrogenation.
J Org Chem
; 73(4): 1639-42, 2008 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18186647
14.
An efficient chemoenzymatic approach to (S)-gamma-fluoroleucine ethyl ester.
J Org Chem
; 70(6): 2372-5, 2005 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-15760235
15.
Palladium-catalyzed regioselective arylation of imidazo[1,2-b][1,2,4]triazine: synthesis of an alpha 2/3-selective GABA agonist.
J Org Chem
; 70(15): 5938-45, 2005 Jul 22.
Artigo
Inglês
| MEDLINE | ID: mdl-16018689
16.
Intramolecular cycloadditions of cyclobutadiene with dienes: experimental and computational studies of the competing (2 + 2) and (4 + 2) modes of reaction.
J Am Chem Soc
; 125(52): 16310-21, 2003 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-14692772
17.
Intramolecular cycloadditions of cyclobutadiene with olefins.
J Am Chem Soc
; 124(49): 14748-58, 2002 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-12465988