Detalhe da pesquisa
1.
Identification of a novel extracellular inhibitor of FGF2/FGFR signaling axis by combined virtual screening and NMR spectroscopy approach.
Bioorg Chem
; 136: 106529, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37084585
2.
Structural Insights into the Ligand-LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents.
Molecules
; 28(6)2023 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36985513
3.
Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies.
Chirality
; 34(3): 498-513, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34962318
4.
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells.
Int J Mol Sci
; 23(21)2022 Oct 27.
Artigo
Inglês
| MEDLINE | ID: mdl-36361848
5.
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer.
Molecules
; 27(14)2022 Jul 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35889200
6.
Enantiomeric Resolution and Absolute Configuration of a Chiral δ-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds.
Molecules
; 25(24)2020 Dec 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33352660
7.
Pyrrolomycins as antimicrobial agents. Microwave-assisted organic synthesis and insights into their antimicrobial mechanism of action.
Bioorg Med Chem
; 27(5): 721-728, 2019 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30711310
8.
Biophysical Assays for Investigating Modulators of Macromolecular Complexes: An Overview.
ACS Omega
; 9(16): 17691-17705, 2024 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38680367
9.
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers.
J Pharm Biomed Anal
; 239: 115902, 2024 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38101238
10.
Identification of HuR-RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization.
ACS Med Chem Lett
; 14(11): 1509-1516, 2023 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37970588
11.
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain.
Pharmaceuticals (Basel)
; 16(7)2023 Jul 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37513874
12.
Urea-based anticancer agents. Exploring 100-years of research with an eye to the future.
Front Chem
; 10: 995351, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36186578
13.
A Composite Nanosystem as a Potential Tool for the Local Treatment of Glioblastoma: Chitosan-Coated Solid Lipid Nanoparticles Embedded in Electrospun Nanofibers.
Polymers (Basel)
; 13(9)2021 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33922214
14.
Sigma-1 receptor antagonists: promising players in fighting neuropathic pain.
Pharm Pat Anal
; 9(3): 77-85, 2020 May.
Artigo
Inglês
| MEDLINE | ID: mdl-32539668
15.
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities.
J Med Chem
; 63(24): 15243-15257, 2020 12 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33152241
16.
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents.
Front Chem
; 8: 495, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32695745
17.
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application.
ACS Med Chem Lett
; 11(5): 883-888, 2020 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32435400