Detalhe da pesquisa
1.
The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity.
Nat Immunol
; 18(5): 519-529, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28346409
2.
IRE1α inhibits osteogenic differentiation of mouse embryonic fibroblasts by limiting Shh signaling.
Oral Dis
; 2024 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38438324
3.
The ER stress sensor inositol-requiring enzyme 1α in Kupffer cells promotes hepatic ischemia-reperfusion injury.
J Biol Chem
; 298(1): 101532, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34953853
4.
Phosphorylation at Ser724 of the ER stress sensor IRE1α governs its activation state and limits ER stress-induced hepatosteatosis.
J Biol Chem
; 298(6): 101997, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35500653
5.
Hypoxic ER stress suppresses ß-catenin expression and promotes cooperation between the transcription factors XBP1 and HIF1α for cell survival.
J Biol Chem
; 294(37): 13811-13821, 2019 09 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31350332
6.
Dual role for inositol-requiring enzyme 1α in promoting the development of hepatocellular carcinoma during diet-induced obesity in mice.
Hepatology
; 68(2): 533-546, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29506314
7.
Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
J Biol Chem
; 290(42): 25756-65, 2015 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26296882
8.
Reduction-responsive cholesterol-based block copolymer vesicles for drug delivery.
Biomacromolecules
; 15(6): 2206-17, 2014 Jun 09.
Artigo
Inglês
| MEDLINE | ID: mdl-24801808
9.
Mammalian IRE1α dynamically and functionally coalesces with stress granules.
Nat Cell Biol
; 2024 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38714852
10.
Polymersomes with PEG corona: structural changes and controlled release induced by temperature variation.
Langmuir
; 29(5): 1356-69, 2013 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-23293844
11.
Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis.
Nat Metab
; 4(9): 1166-1184, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36123394
12.
IRE1α regulates skeletal muscle regeneration through Myostatin mRNA decay.
J Clin Invest
; 2021 Jul 20.
Artigo
Inglês
| MEDLINE | ID: mdl-34283807
13.
Cyclin K and cyclin D1b are oncogenic in myeloma cells.
Mol Cancer
; 9: 103, 2010 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-20459741
14.
A novel iodomethylene-dimethyl-dihydropyranone induces G2/M arrest and apoptosis in human cancer cells.
Anticancer Res
; 29(6): 1963-9, 2009 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-19528453
15.
New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities.
J Med Chem
; 51(12): 3414-21, 2008 Jun 26.
Artigo
Inglês
| MEDLINE | ID: mdl-18503262
16.
Synthesis and antitumor activity of benzils related to combretastatin A-4.
Bioorg Med Chem Lett
; 18(11): 3266-71, 2008 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18477509
17.
Overexpression of the angiogenic tetrapeptide AcSDKP in human malignant tumors.
Anticancer Res
; 28(5A): 2813-7, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-19035315
18.
Inhibition of neddylation by MLN4924 improves neointimal hyperplasia and promotes apoptosis of vascular smooth muscle cells through p53 and p62.
Cell Death Differ
; 25(2): 319-329, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29027989
19.
Tetrapeptide AcSDKP induces postischemic neovascularization through monocyte chemoattractant protein-1 signaling.
Arterioscler Thromb Vasc Biol
; 26(4): 773-9, 2006 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-16410461
20.
Evidence for an association of high levels of endogenous Acetyl-Ser-Asp-Lys-Pro, a potent mediator of angiogenesis, with acute myeloid leukemia development.
Leuk Lymphoma
; 47(9): 1915-20, 2006 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17065006