Detalhe da pesquisa
1.
Targeting ATP-binding site of WRN Helicase: Identification of novel inhibitors through pocket analysis and Molecular Dynamics-Enhanced virtual screening.
Bioorg Med Chem Lett
; 104: 129711, 2024 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38521175
2.
Discovery of novel selective phosphodiesterase1 inhibitors for the treatment of acute myelogenous leukemia.
Bioorg Chem
; 144: 107114, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38224637
3.
Discovery of Dipyridamole Analogues with Enhanced Metabolic Stability for the Treatment of Idiopathic Pulmonary Fibrosis.
Molecules
; 27(11)2022 May 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35684390
4.
Identification of Novel Quinolin-2(1H)-ones as Phosphodiesterase 1 Inhibitors for the Treatment of Inflammatory Bowel Disease.
J Med Chem
; 66(17): 12468-12478, 2023 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37584424
5.
Structural Modifications of Nimodipine Lead to Novel PDE1 Inhibitors with Anti-pulmonary Fibrosis Effects.
J Med Chem
; 65(12): 8444-8455, 2022 06 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35666471