Detalhe da pesquisa
1.
N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists.
Bioorg Med Chem Lett
; 21(18): 5283-8, 2011 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21802943
2.
Development of substituted 6-[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as potent poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors active in BRCA deficient cells.
Bioorg Med Chem Lett
; 20(3): 1100-5, 2010 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20022747
3.
Discovery of a potent class I selective ketone histone deacetylase inhibitor with antitumor activity in vivo and optimized pharmacokinetic properties.
J Med Chem
; 52(11): 3453-6, 2009 Jun 11.
Artigo
Inglês
| MEDLINE | ID: mdl-19441846
4.
Synthesis of novel fluorescent probes for the molecular chaperone Hsp90.
Bioorg Med Chem Lett
; 13(22): 3975-8, 2003 Nov 17.
Artigo
Inglês
| MEDLINE | ID: mdl-14592488