Detalhe da pesquisa
1.
A novel investigational Fc-modified humanized monoclonal antibody, motavizumab-YTE, has an extended half-life in healthy adults.
Antimicrob Agents Chemother
; 57(12): 6147-53, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24080653
2.
Analysis of respiratory syncytial virus preclinical and clinical variants resistant to neutralization by monoclonal antibodies palivizumab and/or motavizumab.
J Infect Dis
; 203(5): 674-82, 2011 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21208913
3.
A randomized controlled trial of motavizumab versus palivizumab for the prophylaxis of serious respiratory syncytial virus disease in children with hemodynamically significant congenital heart disease.
Pediatr Res
; 70(2): 186-91, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21522037
4.
A phase 2, randomized, double-blind safety and pharmacokinetic assessment of respiratory syncytial virus (RSV) prophylaxis with motavizumab and palivizumab administered in the same season.
BMC Pediatr
; 10: 38, 2010 Jun 03.
Artigo
Inglês
| MEDLINE | ID: mdl-20525274
5.
Safety, tolerability, pharmacokinetics, and immunogenicity of motavizumab, a humanized, enhanced-potency monoclonal antibody for the prevention of respiratory syncytial virus infection in at-risk children.
Pediatr Infect Dis J
; 28(4): 267-72, 2009 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-19258920
6.
Efficacy of motavizumab for the prevention of respiratory syncytial virus disease in healthy Native American infants: a phase 3 randomised double-blind placebo-controlled trial.
Lancet Infect Dis
; 15(12): 1398-408, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26511956
7.
Standard and alternative regimens of Haemophilus influenzae type b conjugate vaccine (polyribosylribitol phosphate-tetanus toxoid conjugate vaccine) elicit comparable antibody avidities in infants.
Pediatr Infect Dis J
; 21(9): 822-6, 2002 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-12352802
8.
Randomized, Double-Blind Study of the Pharmacokinetics and Safety of Palivizumab Liquid Formulation Compared with Lyophilized Formulation.
Infect Dis Ther
; 3(2): 203-14, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25269648
9.
Motavizumab treatment of infants hospitalized with respiratory syncytial virus infection does not decrease viral load or severity of illness.
Pediatr Infect Dis J
; 33(7): 703-9, 2014 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-24356256
10.
Prevalence and Characteristics of Human Metapneumovirus Infection Among Hospitalized Children at High Risk for Severe Lower Respiratory Tract Infection.
J Pediatric Infect Dis Soc
; 1(3): 212-22, 2012 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26619409
11.
Motavizumab for prophylaxis of respiratory syncytial virus in high-risk children: a noninferiority trial.
Pediatrics
; 125(1): e35-51, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20008423
12.
Safety and antiviral activity of motavizumab, a respiratory syncytial virus (RSV)-specific humanized monoclonal antibody, when administered to RSV-infected children.
Pediatr Infect Dis J
; 28(9): 835-7, 2009 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-19636278
13.
Development of a PIV-vectored RSV vaccine: preclinical evaluation of safety, toxicity, and enhanced disease and initial clinical testing in healthy adults.
Vaccine
; 26(50): 6373-82, 2008 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-18822334
14.
B cell responses in gastric antrum and duodenum following oral inactivated Helicobacter pylori whole cell (HWC) vaccine and LT(R192G) in H pylori seronegative individuals.
Vaccine
; 21(5-6): 562-5, 2003 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-12531656
15.
Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers.
Clin Immunol
; 108(3): 241-7, 2003 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-14499247
16.
Phase I evaluation of delta virG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adults.
Infect Immun
; 70(4): 2016-21, 2002 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-11895966