Detalhe da pesquisa
1.
Targeting DNA polymerase to DNA double-strand breaks reduces DNA deletion size and increases templated insertions generated by CRISPR/Cas9.
Nucleic Acids Res
; 50(7): 3944-3957, 2022 04 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35323942
2.
New Advances in Using Virus-like Particles and Related Technologies for Eukaryotic Genome Editing Delivery.
Int J Mol Sci
; 23(15)2022 Aug 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35955895
3.
Delivering Cas9/sgRNA ribonucleoprotein (RNP) by lentiviral capsid-based bionanoparticles for efficient 'hit-and-run' genome editing.
Nucleic Acids Res
; 47(17): e99, 2019 09 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31299082
4.
Delivering SaCas9 mRNA by lentivirus-like bionanoparticles for transient expression and efficient genome editing.
Nucleic Acids Res
; 47(8): e44, 2019 05 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30759231
5.
CRISPR/Cas9 increases mitotic gene conversion in human cells.
Gene Ther
; 27(6): 281-296, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32020049
6.
Mitochondria-targeted antioxidant SkQ1 improves spermatogenesis in Immp2l mutant mice.
Andrologia
; 50(2)2018 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-28703400
7.
Oocyte-Specific Expression of Mouse MEX3C652AA in the Ovary and Its Potential Role in Regulating Maternal Fos mRNA.
Biol Reprod
; 94(5): 115, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27053362
8.
Renal antiporter ClC-5 regulates collagen I/IV through the ß-catenin pathway and lysosomal degradation.
Life Sci Alliance
; 7(7)2024 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-38670633
9.
Virus-like particle-based delivery of Cas9/guide RNA ribonucleoprotein efficiently edits the brachyury gene and inhibits chordoma growth in vivo.
Discov Oncol
; 14(1): 70, 2023 May 18.
Artigo
Inglês
| MEDLINE | ID: mdl-37198417
10.
Immp2l Mutation Induces Mitochondrial Membrane Depolarization and Complex III Activity Suppression after Middle Cerebral Artery Occlusion in Mice.
Curr Med Sci
; 43(3): 478-488, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-37243806
11.
Detection of lineage-reprogramming efficiency of tumor cells in a 3D-printed liver-on-a-chip model.
Theranostics
; 13(14): 4905-4918, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37771785
12.
Developing all-in-one virus-like particles for Cas9 mRNA/single guide RNA co-delivery and aptamer-containing lentiviral vectors for improved gene expression.
Int J Biol Macromol
; 209(Pt A): 1260-1270, 2022 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35461863
13.
Lentiviral vector mediated gene therapy for type I Dent disease ameliorates Dent disease-like phenotypes for three months in ClC-5 null mice.
Mol Ther Methods Clin Dev
; 27: 149-166, 2022 Dec 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36284768
14.
The gRNA Vector Level Determines the Outcome of Systemic AAV CRISPR Therapy for Duchenne Muscular Dystrophy.
Hum Gene Ther
; 33(9-10): 518-528, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35350865
15.
Deficiency in the inner mitochondrial membrane peptidase 2-like (Immp21) gene increases ischemic brain damage and impairs mitochondrial function.
Neurobiol Dis
; 44(3): 270-6, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21824519
16.
Heterochronic Parabiosis: Old Blood Induces Changes in Mitochondrial Structure and Function of Young Mice.
J Gerontol A Biol Sci Med Sci
; 76(3): 434-439, 2021 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33377482
17.
Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing.
J Extracell Vesicles
; 10(5): e12076, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33747370
18.
Lentiviral Capsid-Mediated Streptococcus pyogenes Cas9 Ribonucleoprotein Delivery for Efficient and Safe Multiplex Genome Editing.
CRISPR J
; 4(6): 914-928, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33733873
19.
3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts.
Biomaterials
; 269: 120668, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33461059
20.
Adenine Base Editor Ribonucleoproteins Delivered by Lentivirus-Like Particles Show High On-Target Base Editing and Undetectable RNA Off-Target Activities.
CRISPR J
; 4(1): 69-81, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33616436