Detalhe da pesquisa
1.
Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aß oligomers.
Proc Natl Acad Sci U S A
; 119(49): e2210766119, 2022 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36442093
2.
Prostaglandin F2α and angiotensin II type 1 receptors exhibit differential cognate G protein coupling regulation.
J Biol Chem
; 298(9): 102294, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35872018
3.
Pharmacodynamic characterization of rytvela, a novel allosteric anti-inflammatory therapeutic, to prevent preterm birth and improve fetal and neonatal outcomes.
Am J Obstet Gynecol
; 228(4): 467.e1-467.e16, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36244408
4.
1,3,5,8-Tetrasubstituted 1,3,4-Benzotriazepin-2-one Scaffolds for ß-Turn Mimicry without Stereogenic Carbon Centers: Synthesis and Conformational Analysis.
J Org Chem
; 88(7): 4633-4648, 2023 Apr 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36930829
5.
Synthesis of 5- and 7-hydroxy indolizidin-2-one prostaglandin-F2α modulators and activity on myometrial contractility towards development of agents for delaying preterm birth.
J Pept Sci
; 29(3): e3455, 2023 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-36184819
6.
Synthesis and biological evaluation of novel all-hydrocarbon cross-linked aza-stapled peptides.
Org Biomol Chem
; 20(40): 7963-7971, 2022 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-36190455
7.
Constrained Dipeptide Surrogates: 5- and 7-Hydroxy Indolizidin-2-one Amino Acid Synthesis from Iodolactonization of Dehydro-2,8-diamino Azelates.
Molecules
; 27(1)2021 Dec 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35011297
8.
Influence of N-Methylation and Conformation on Almiramide Anti-Leishmanial Activity.
Molecules
; 26(12)2021 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34204673
9.
Stereo- and Regiochemical Transannular Cyclization of a Common Hexahydro-1H-azonine to Afford Three Different Indolizidinone Dipeptide Mimetics.
J Org Chem
; 85(3): 1340-1351, 2020 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31642317
10.
Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila.
PLoS Genet
; 13(4): e1006694, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28406902
11.
Applications of γ,δ-Unsaturated Ketones Synthesized by Copper-Catalyzed Cascade Addition of Vinyl Grignard Reagents to Esters.
Acc Chem Res
; 51(10): 2574-2588, 2018 10 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30289682
12.
Adiponectin has a pivotal role in the cardioprotective effect of CP-3(iv), a selective CD36 azapeptide ligand, after transient coronary artery occlusion in mice.
FASEB J
; 32(2): 807-818, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29018142
13.
Heumann Indole Flow Chemistry Process.
J Org Chem
; 84(17): 10929-10937, 2019 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31314527
14.
Solid-Phase Azopeptide Diels-Alder Chemistry for Aza-pipecolyl Residue Synthesis To Study Peptide Conformation.
J Org Chem
; 84(10): 6006-6016, 2019 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-30957495
15.
Antenatal Suppression of IL-1 Protects against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice.
J Immunol
; 198(5): 2047-2062, 2017 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28148737
16.
Application of N-Dodecyl l-Peptide to Enhance Serum Stability while Maintaining Inhibitory Effects on Myometrial Contractions Ex Vivo.
Molecules
; 24(22)2019 Nov 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31731725
17.
Azapeptide Synthesis Methods for Expanding Side-Chain Diversity for Biomedical Applications.
Acc Chem Res
; 50(7): 1541-1556, 2017 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28598597
18.
4-Vinylproline.
J Org Chem
; 83(21): 13580-13586, 2018 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30247028
19.
Urotensin core mimics that modulate the biological activity of urotensin-II related peptide but not urotensin-II.
Bioorg Med Chem Lett
; 27(15): 3412-3416, 2017 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28625362
20.
Aza-amino acid scanning of chromobox homolog 7 (CBX7) ligands.
J Pept Sci
; 23(4): 266-271, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-28220557