Detalhe da pesquisa
1.
Structural dynamics and allostery of Rab proteins: strategies for drug discovery and design.
Brief Bioinform
; 22(1): 270-287, 2021 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31950981
2.
Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites.
Proteins
; 86(3): 301-321, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29235148
3.
Inhibition of Human Amylin Aggregation and Cellular Toxicity by Lipoic Acid and Ascorbic Acid.
Mol Pharm
; 15(6): 2098-2106, 2018 06 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29709194
4.
Discovery of Rab1 binding sites using an ensemble of clustering methods.
Proteins
; 85(5): 859-871, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28120477
5.
R248Q mutation--Beyond p53-DNA binding.
Proteins
; 83(12): 2240-50, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26442703
6.
Exploiting protein intrinsic flexibility in drug design.
Adv Exp Med Biol
; 805: 245-69, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24446365
7.
Conformational dynamics of capping protein and interaction partners: simulation studies.
Proteins
; 80(4): 1066-77, 2012 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-22253039
8.
The distinct conformational dynamics of K-Ras and H-Ras A59G.
PLoS Comput Biol
; 6(9)2010 Sep 09.
Artigo
Inglês
| MEDLINE | ID: mdl-20838576
9.
Inhibition of lysozyme aggregation and cellular toxicity by organic acids at acidic and physiological pH conditions.
Int J Biol Macromol
; 149: 921-930, 2020 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32001287
10.
Aggregation and Cellular Toxicity of Pathogenic or Non-pathogenic Proteins.
Sci Rep
; 10(1): 5120, 2020 03 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32198463
11.
A network of dynamically conserved residues deciphers the motions of maltose transporter.
Proteins
; 76(3): 588-97, 2009 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19274733
12.
Computational and Experimental Approaches to Design Inhibitors of Amylin Aggregation.
Curr Drug Targets
; 20(16): 1680-1694, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31333136
13.
Allosteric binding sites in Rab11 for potential drug candidates.
PLoS One
; 13(6): e0198632, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29874286
14.
Computational methods for Traditional Chinese Medicine: a survey.
Comput Methods Programs Biomed
; 88(3): 283-94, 2007 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-17983685
15.
Mapping the structural and dynamical features of multiple p53 DNA binding domains: insights into loop 1 intrinsic dynamics.
PLoS One
; 8(11): e80221, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-24324553
16.
Novel allosteric sites on Ras for lead generation.
PLoS One
; 6(10): e25711, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-22046245
17.
Unraveling evolutionary constraints: a heterogeneous conservation in dynamics of the titin Ig domains.
FEBS Lett
; 584(6): 1235-9, 2010 Mar 19.
Artigo
Inglês
| MEDLINE | ID: mdl-20171214