Detalhe da pesquisa
1.
All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.
Blood
; 127(23): 2867-78, 2016 06 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27103744
2.
Crenolanib is a potent inhibitor of FLT3 with activity against resistance-conferring point mutants.
Blood
; 123(1): 94-100, 2014 Jan 02.
Artigo
Inglês
| MEDLINE | ID: mdl-24227820
3.
TTT-3002 is a novel FLT3 tyrosine kinase inhibitor with activity against FLT3-associated leukemias in vitro and in vivo.
Blood
; 123(10): 1525-34, 2014 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-24408321
4.
FLT3/D835Y mutation knock-in mice display less aggressive disease compared with FLT3/internal tandem duplication (ITD) mice.
Proc Natl Acad Sci U S A
; 110(52): 21113-8, 2013 Dec 24.
Artigo
Inglês
| MEDLINE | ID: mdl-24255108
5.
Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell-cold solid tumors.
Sci Transl Med
; 13(608)2021 08 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34433637
6.
A CD40 Agonist and PD-1 Antagonist Antibody Reprogram the Microenvironment of Nonimmunogenic Tumors to Allow T-cell-Mediated Anticancer Activity.
Cancer Immunol Res
; 7(3): 428-442, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30642833
7.
Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3.
Oncotarget
; 9(68): 32885-32899, 2018 Aug 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30250637
8.
Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs.
Cancer Immunol Res
; 6(12): 1561-1577, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30341213
9.
FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors.
Oncotarget
; 8(7): 10931-10944, 2017 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28077790
10.
Adaptation to TKI Treatment Reactivates ERK Signaling in Tyrosine Kinase-Driven Leukemias and Other Malignancies.
Cancer Res
; 77(20): 5554-5563, 2017 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28923853
11.
Potential role for all-trans retinoic acid in nonpromyelocytic acute myeloid leukemia.
Int J Hematol Oncol
; 5(4): 133-142, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30302214
12.
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
Sci Transl Med
; 7(291): 291ra96, 2015 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26062848
13.
FLT3 kinase inhibitor TTT-3002 overcomes both activating and drug resistance mutations in FLT3 in acute myeloid leukemia.
Cancer Res
; 74(18): 5206-17, 2014 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25060518