Detalhe da pesquisa
1.
Efficacy and safety of ETC-1002, a novel investigational low-density lipoprotein-cholesterol-lowering therapy for the treatment of patients with hypercholesterolemia and type 2 diabetes mellitus.
Arterioscler Thromb Vasc Biol
; 34(3): 676-83, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24385236
2.
Phase 1, Single- and Multiple-Ascending-Dose, Food-Effect, and East Asian Subject Studies to Assess the Pharmacokinetics, Safety, and Tolerability of Bempedoic Acid, a Selective Inhibitor of Adenosine Triphosphate Citrate Lyase.
Clin Pharmacol Drug Dev
; 12(10): 1022-1035, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37477389
3.
Absence of effect of steady state bempedoic acid on cardiac repolarization: Results of a thorough QT/QTc study in healthy volunteers.
Clin Transl Sci
; 14(6): 2487-2496, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34463032
4.
Combination of bempedoic acid, ezetimibe, and atorvastatin in patients with hypercholesterolemia: A randomized clinical trial.
Atherosclerosis
; 320: 122-128, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33514449
5.
Lipid lowering with bempedoic acid added to a proprotein convertase subtilisin/kexin type 9 inhibitor therapy: A randomized, controlled trial.
J Clin Lipidol
; 15(4): 593-601, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34172394
6.
Complementary low-density lipoprotein-cholesterol lowering and pharmacokinetics of adding bempedoic acid (ETC-1002) to high-dose atorvastatin background therapy in hypercholesterolemic patients: A randomized placebo-controlled trial.
J Clin Lipidol
; 13(4): 568-579, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31202641
7.
Trends in Patient Access to and Utilization of Prescribed PCSK9 Inhibitors in a Large US Claims Database From 2015 to 2021.
Circ Cardiovasc Qual Outcomes
; 17(2): e009988, 2024 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38362767
8.
Effect of ETC-1002 on Serum Low-Density Lipoprotein Cholesterol in Hypercholesterolemic Patients Receiving Statin Therapy.
Am J Cardiol
; 117(12): 1928-33, 2016 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27138185
9.
Treatment with ETC-1002 alone and in combination with ezetimibe lowers LDL cholesterol in hypercholesterolemic patients with or without statin intolerance.
J Clin Lipidol
; 10(3): 556-67, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27206943
10.
Use of ETC-1002 to treat hypercholesterolemia in patients with statin intolerance.
J Clin Lipidol
; 9(3): 295-304, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26073387
11.
Effectiveness and tolerability of a new lipid-altering agent, gemcabene, in patients with low levels of high-density lipoprotein cholesterol.
Am J Cardiol
; 92(5): 538-43, 2003 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-12943873
12.
Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase in patients with hypercholesterolemia: results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial.
J Am Coll Cardiol
; 62(13): 1154-62, 2013 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23770179