Detalhe da pesquisa
1.
Oral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease : A Randomized Controlled Trial.
Ann Intern Med
; 175(12): 1666-1674, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36343348
2.
A prospective multicenter observational study of cell-mediated immunity as a predictor for cytomegalovirus infection in kidney transplant recipients.
Am J Transplant
; 19(9): 2505-2516, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30768834
3.
A pooled analysis of adverse events in 393 adults with Gaucher disease type 1 from four clinical trials of oral eliglustat: Evaluation of frequency, timing, and duration.
Blood Cells Mol Dis
; 68: 185-191, 2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28126395
4.
Two randomized trials of linaclotide for chronic constipation.
N Engl J Med
; 365(6): 527-36, 2011 Aug 11.
Artigo
Inglês
| MEDLINE | ID: mdl-21830967
5.
Effect of linaclotide on severe abdominal symptoms in patients with irritable bowel syndrome with constipation.
Clin Gastroenterol Hepatol
; 12(4): 616-23, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24075889
6.
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Gastroenterology
; 145(6): 1334-46.e1-11, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23958540
7.
Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.
Am J Gastroenterol
; 107(11): 1702-12, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22986437
8.
A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation.
Am J Gastroenterol
; 107(11): 1714-24; quiz p.1725, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22986440
9.
Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation.
Gastroenterology
; 139(6): 1877-1886.e2, 2010 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20801122
10.
Efficacy of linaclotide for patients with chronic constipation.
Gastroenterology
; 138(3): 886-95.e1, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20045700
11.
Disease-modifying effects of edasalonexent, an NF-κB inhibitor, in young boys with Duchenne muscular dystrophy: Results of the MoveDMD phase 2 and open label extension trial.
Neuromuscul Disord
; 31(5): 385-396, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33678513
12.
A Randomized, Double-Blind, Placebo-Controlled, Global Phase 3 Study of Edasalonexent in Pediatric Patients with Duchenne Muscular Dystrophy: Results of the PolarisDMD Trial.
J Neuromuscul Dis
; 8(5): 769-784, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34120912
13.
Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial.
JAMA Neurol
; 77(5): 582-592, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32065623
14.
Pilot study on the effect of linaclotide in patients with chronic constipation.
Am J Gastroenterol
; 104(1): 125-32, 2009 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19098860
15.
Randomised clinical trial: a placebo-controlled study of subcutaneous or intradermal NEXVAX2, an investigational immunomodulatory peptide therapy for coeliac disease.
Aliment Pharmacol Ther
; 50(5): 547-555, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31407810
16.
Elevated serum interleukin-2 after gluten correlates with symptoms and is a potential diagnostic biomarker for coeliac disease.
Aliment Pharmacol Ther
; 50(8): 901-910, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31483515
17.
Differentiating Familial Chylomicronemia Syndrome From Multifactorial Severe Hypertriglyceridemia by Clinical Profiles.
J Endocr Soc
; 3(12): 2397-2410, 2019 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31777768
18.
Utility of the T-SPOT®.TB test's borderline category to increase test resolution for results around the cut-off point.
Tuberculosis (Edinb)
; 108: 178-185, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29523321
19.
Soft x-ray spectroscopy of high pressure liquid.
Rev Sci Instrum
; 89(1): 013114, 2018 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-29390687
20.
Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study.
EBioMedicine
; 26: 78-90, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-29191561