Detalhe da pesquisa
1.
Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPß phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea.
J Enzyme Inhib Med Chem
; 39(1): 2287420, 2024 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38058285
2.
2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms.
J Enzyme Inhib Med Chem
; 38(1): 2270183, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37870190
3.
Anticancer Activity of Sunitinib Analogues in Human Pancreatic Cancer Cell Cultures under Normoxia and Hypoxia.
Int J Mol Sci
; 24(6)2023 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36982496
4.
Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment.
Bioorg Chem
; 128: 106071, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-35932498
5.
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase-associated RNase H function.
J Enzyme Inhib Med Chem
; 36(1): 749-757, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33715562
6.
Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives.
J Enzyme Inhib Med Chem
; 36(1): 685-692, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33602041
7.
Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions.
Molecules
; 26(13)2021 Jun 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34201561
8.
Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
Inglês
| MEDLINE | ID: mdl-32366711
9.
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation.
J Enzyme Inhib Med Chem
; 35(1): 539-548, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31948300
10.
Ferulic Acid Esters and Withanolides: In Search of Withania somnifera GABAA Receptor Modulators.
J Nat Prod
; 82(5): 1250-1257, 2019 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-30998355
11.
Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases.
J Enzyme Inhib Med Chem
; 34(1): 1526-1533, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31431095
12.
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors.
J Enzyme Inhib Med Chem
; 34(1): 55-74, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-30362381
13.
Identification of Myricetin as an Ebola Virus VP35-Double-Stranded RNA Interaction Inhibitor through a Novel Fluorescence-Based Assay.
Biochemistry
; 57(44): 6367-6378, 2018 11 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30298725
14.
Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
Nucleic Acids Res
; 44(5): 2310-22, 2016 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-26850643
15.
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1329-1340, 2017 May.
Artigo
Inglês
| MEDLINE | ID: mdl-28025082
16.
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders.
J Nat Prod
; 80(10): 2799-2806, 2017 10 27.
Artigo
Inglês
| MEDLINE | ID: mdl-29039946
17.
Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase.
J Enzyme Inhib Med Chem
; 32(1): 130-136, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-27766892
18.
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B.
J Enzyme Inhib Med Chem
; 32(1): 264-270, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-28097874
19.
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors.
J Enzyme Inhib Med Chem
; 32(1): 68-73, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-27775452
20.
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida.
J Enzyme Inhib Med Chem
; 31(6): 1672-7, 2016 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26745285