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1.
Support Care Cancer ; 27(9): 3625, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31161435

RESUMO

There is a typo in the Funding reference cited in the paper. This alteration is fundamental to justify the funding of the project.

2.
Support Care Cancer ; 25(10): 3059-3066, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28455545

RESUMO

PURPOSE: We aimed to assess the factor structure, internal consistency, test-retest reliability, and construct validity of the European Portuguese version of the Pittsburgh Sleep Quality Index (PSQI) in breast cancer patients. METHODS: This study was based on a cohort of breast cancer patients, among whom the PSQI was used to measure sleep quality three years after cancer diagnosis (N = 474). A sample of 62 participants underwent additional PSQI testing, wore a wrist actigraph for five consecutive days, and was reevaluated with the PSQI after one month. A confirmatory factor analysis, considering the components suggested by the principal component analysis (PCA), was performed to determine model fit. To evaluate internal consistency and test-retest reliability, Cronbach's alpha and intraclass correlation coefficient (ICC) were calculated, respectively. To assess construct validity, Spearman's correlation coefficients were computed between PSQI scores and actigraphy measures and other theoretical related constructs. RESULTS: PCA suggested one or two components. The latter showed better fit to the data, though the two factors were strongly correlated (r = 0.76) and internal consistency was not satisfactory for one of the factors. Regarding the one-factor model, internal consistency (Cronbach's alpha = 0.70) and test-retest reliability (ICC = 0.76) were adequate. Sleep duration, habitual sleep efficiency, and sleep disturbance dimensions were significantly correlated with the corresponding actigraphy measures; the PSQI global score derived from the one-factor model was more strongly correlated with subjective sleep complaints (r ≥ 0.60). CONCLUSIONS: The unidimensional construct of the European Portuguese version of the PSQI showed adequate reliability and validity among breast cancer patients.


Assuntos
Neoplasias da Mama/fisiopatologia , Neoplasias da Mama/psicologia , Indicadores Básicos de Saúde , Psicometria/métodos , Transtornos do Sono-Vigília/diagnóstico , Sono/fisiologia , Adulto , Idoso , Neoplasias da Mama/complicações , Estudos de Coortes , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Reprodutibilidade dos Testes , Transtornos do Sono-Vigília/fisiopatologia , Transtornos do Sono-Vigília/psicologia , Inquéritos e Questionários
3.
GE Port J Gastroenterol ; 28(4): 243-252, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34386553

RESUMO

INTRODUCTION: Risk stratification in patients with nonvariceal upper gastrointestinal bleeding (NVUGIB) is crucial for proper management. Rockall score (RS; pre-endoscopic and complete) and Glasgow-Blatchford score (GBS) are some of the most used scoring systems. This study aims to analyze these scores' ability to predict various clinical outcomes and possible cutoff points to identify low- and high-risk patients. Secondarily, this study intents to evaluate the appropriateness of patients' transfers to our facility, which provides a specialized emergency endoscopy service. METHODS: This study was retrospectively conducted at Centro Hospitalar Universitário do Porto and included patients admitted to the Emergency Department with acute manifestations of NVUGIB between January 2016 and December 2018. Receiver operating characteristic (ROC) curves and corresponding areas under the curve (AUC) were calculated. Transferred patients from other institutions and nontransferred (directly admitted to this institution) patients were also compared. RESULTS: Of a total of 420 patients, 23 (5.9%) died, 34 (8.4%) rebled, 217 (51.7%) received blood transfusion, 153 (36.3%) received endoscopic therapy, 22 (5.7%) had surgery, and 171 (42.3%) required hospitalization in the Intermediate or Intensive Care Unit. Regarding mortality prediction, both complete RS (AUC 0.756, p < 0.001) and pre-endoscopic RS (AUC 0.711, p = 0.001) showed good performance. In the prediction of rebleeding, only complete RS (AUC 0.735, p < 0.001) had discriminative ability. GBS had good performance in the prediction of transfusion (AUC 0.785, p < 0.001). No score showed discriminative capability in the prediction of other outcomes. Transferred and nontransferred patients had similar pre-endoscopic RS (3.41 vs. 3.34, p = 0.692) and GBS (13.29 vs. 12.29, p = 0.056). Only patients with GBS ≥6 were transferred to our facility. There were no adverse outcomes recorded in any group when GBS was ≤3. DISCUSSION/CONCLUSION: Complete RS and pre-endoscopic RS are effective at predicting mortality, but only complete RS showed good performance at predicting rebleeding. GBS is better at predicting transfusion requirement. Our study suggests that a transfer can possibly be reconsidered if GBS is ≤3, although current recommendations only propose outpatient care when GBS is 0 or 1. Patients' transfers were appropriate, considering the high GBS scores and the outcomes of these patients.


INTRODUÇÃO: A gestão adequada de doentes com hemorragia digestiva alta não hipertensiva requer uma estratificação do risco apropriada, sendo o score de Rockall (RS; pré-endoscópico e completo) e o score de Glasgow-Blatchford (GBS) frequentemente usados. Um dos objetivos deste estudo é avaliar o seu valor prognóstico e identificar possíveis pontos de corte que identifiquem doentes de alto e baixo risco. Também se pretende analisar se as transferências de doentes para o nosso hospital são adequadas, uma vez que é nesta instituição que decorre a urgência regional noturna de Gastroenterologia. MÉTODOS: Realizada análise retrospetiva dos doentes admitidos no Serviço de Urgência do Centro Hospitalar Universitário do Porto (CHUP) com hemorragia digestiva alta não hipertensiva desde janeiro de 2016 a dezembro de 2018. A análise foi baseada nas curvas de característica de operação do recetor (ROC) e respetivas áreas (AUC). O grupo de doentes transferidos de outros hospitais para o CHUP foi comparado com o grupo de doentes diretamente admitidos. RESULTADOS: De um total de 420 doentes, 23 (5.9%) morreram, 34 (8.4%) tiveram recidiva hemorrágica, 217 (51.7%) receberam transfusão de sangue, 153 (36.3%) foram tratados endoscopicamente, 22 (5.7%) foram submetidos a cirurgia e 171 (42.3%) ficaram hospitalizados na Unidade de Cuidados Intermédios ou Intensivos. Tanto o RS completo (AUC 0.756, p < 0.001) como o pré-endoscópico (AUC 0.711, p = 0.001) conseguiram prever a mortalidade. Apenas o RS completo (AUC 0.735, p < 0.001) mostrou bom desempenho na previsão da recidiva. O GBS teve bom desempenho na previsão de transfusão (AUC 0.785, p < 0.001). Nenhum dos scores mostrou capacidade de prever outras necessidades. Os doentes transferidos apresentaram RS pré-endoscópico (3.41 vs. 3.34, p = 0.692) e GBS (13.29 vs. 12.29, p = 0.056) semelhantes aos diretamente admitidos. Apenas doentes com GBS ≥6 foram transferidos. Não existe registo de qualquer evento adverso com GBS ≤3. DISCUSSÃO/CONCLUSÃO: O RS completo e pré-endoscópico são eficazes a prever a mortalidade, mas apenas o RS completo consegue prever recidiva hemorrágica. O GBS consegue prever necessidade de transfusão. O nosso estudo sugere que, perante um doente com GBS de 3 ou inferior, a transferência poderá ser reconsiderada, no entanto, as recomendações atuais apenas sugerem gestão em ambulatório quando o GBS é 0 ou 1. As transferências feitas para o CHUP revelaram-se necessárias, pois os doentes apresentaram GBS altos e taxas de eventos adversos significativas.

4.
J Exp Psychol Anim Learn Cogn ; 44(1): 67-81, 2018 01.
Artigo em Inglês | MEDLINE | ID: mdl-29154562

RESUMO

Allan and collaborators (Allan, Hannah, Crump, & Siegel, 2008; Allan, Siegel, & Tangen, 2005; Siegel, Allan, Hannah, & Crump, 2009) recently proposed to apply signal detection theory to the analysis of contingency judgment tasks. When exposed to a flow of stimuli, participants are asked to judge whether there is a contingent relation between a cue and an outcome, that is, whether the subjective cue-outcome contingency exceeds a decision threshold. In this context, we tested the following hypotheses regarding the relation between objective and subjective cue-outcome contingency: (a) The underlying distributions of subjective cue-outcome contingency are Gaussian; (b) The mean distribution of subjective contingency is a linear function of objective cue-outcome contingency; and (c) The variance in the distribution of subjective contingency is constant. The hypotheses were tested by combining a streamed-trial contingency assessment task with a confidence rating procedure. Participants were exposed to rapid flows of stimuli at the end of which they had to judge whether an outcome was more (Experiment 1) or less (Experiment 2) likely to appear following a cue and how sure they were of their judgment. We found that although Hypothesis A seems reasonable, Hypotheses B and C were not. Regarding Hypothesis B, participants were more sensitive to positive than to negative contingencies. Regarding Hypothesis C, the perceived cue-outcome contingency became more variable when the contingency became more positive or negative, but only to a slight extent. (PsycINFO Database Record


Assuntos
Aprendizagem por Associação/fisiologia , Psicofísica , Adolescente , Adulto , Sinais (Psicologia) , Feminino , Humanos , Masculino , Distribuição Normal , Psicometria , Adulto Jovem
5.
Behav Processes ; 81(2): 280-5, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19022356

RESUMO

We examined if the representation of time intervals in a temporal discrimination task is based not only on their absolute but also on their relative durations. Six pigeons learned two temporal discriminations. In the first, red and green choices were correct following 2-s and 8-s samples, respectively. In the second, vertical and horizontal bar choices were correct following 4-s and 16-s samples, respectively. In a previous study [Zentall, T.R., Weaver, J.E., Clement, T.S., 2004. Pigeons group time intervals according to their relative duration. Psychon. Bull. Rev. 11, 113-117.], tests with 4-s samples and red/green comparisons revealed a bias for red, whereas tests with 8-s samples with vertical/horizontal comparisons revealed a bias for horizontal. These results were interpreted in terms of relative encoding of sample durations. We attempted to replicate this finding but instead of testing with only 4-s or 8-s samples, we tested with several other sample durations to obtain a psychometric function. Results were inconsistent with the relative encoding hypothesis.


Assuntos
Discriminação Psicológica/fisiologia , Percepção do Tempo/fisiologia , Animais , Columbidae , Condicionamento Operante/fisiologia , Aprendizagem por Discriminação/fisiologia , Generalização Psicológica , Modelos Logísticos , Psicometria , Desempenho Psicomotor/fisiologia
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