Detalhe da pesquisa
1.
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Nature
; 552(7684): 194-199, 2017 12 14.
Artigo
Inglês
| MEDLINE | ID: mdl-29211715
2.
Effect of Sepatronium Bromide (YM-155) on DNA Double-Strand Breaks Repair in Cancer Cells.
Int J Mol Sci
; 21(24)2020 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33322336
3.
Targeting genotoxic and proteotoxic stress-response pathways in human prostate cancer by clinically available PARP inhibitors, vorinostat and disulfiram.
Prostate
; 79(4): 352-362, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30499118
4.
Identification of novel dithiocarbamate-copper complexes targeting p97/NPL4 pathway in cancer cells.
Eur J Med Chem
; 261: 115790, 2023 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37690264
5.
Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway.
Cells
; 9(2)2020 02 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32085572
6.
Expression and purification of recombinant NFI proteins for functional analysis.
Gen Physiol Biophys
; 28(4): 331-9, 2009 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-20097955
7.
Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase.
Oncogene
; 38(40): 6711-6722, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31391554
8.
PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair.
DNA Repair (Amst)
; 78: 114-127, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31009828
9.
Cells and Stripes: A novel quantitative photo-manipulation technique.
Sci Rep
; 6: 19567, 2016 Jan 18.
Artigo
Inglês
| MEDLINE | ID: mdl-26777522
10.
DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer.
Mol Oncol
; 10(6): 879-94, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26987799
11.
Expression, purification and assembly of soluble multimeric MHC class II-invariant chain complexes.
FEBS Lett
; 586(9): 1318-24, 2012 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-22465664
12.
Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft.
FEBS J
; 277(20): 4338-45, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20860624