Detalhe da pesquisa
1.
Synthesis and evaluation of arylpiperazines derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT1AR ligands.
Bioorg Med Chem Lett
; 24(19): 4759-4762, 2014 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25182564
2.
Radiosynthesis of [18F]ATPFU: a potential PET ligand for mTOR.
J Labelled Comp Radiopharm
; 57(13): 705-9, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25359578
3.
Synthesis and in vitro evaluation of [18F]BMS-754807: a potential PET ligand for IGF-1R.
Bioorg Med Chem Lett
; 23(14): 4191-4, 2013 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23743281
4.
Synthesis and in vivo evaluation of [(18)F]2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione ([(18)F]FECUMI-101) as an imaging probe for 5-HT1A receptor agonist in nonhuman primates.
Bioorg Med Chem
; 21(17): 5598-604, 2013 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23816046
5.
Radiosynthesis of [11C]BBAC and [11C]BBPC as potential PET tracers for orexin2 receptors.
Bioorg Med Chem Lett
; 22(6): 2172-4, 2012 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22364813
6.
Synthesis and in vitro evaluation of [18F](R)-FEPAQ: a potential PET ligand for VEGFR2.
Bioorg Med Chem Lett
; 22(15): 5104-7, 2012 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22749281
7.
Comparison of high and low affinity serotonin 1A receptors by PET in vivo in nonhuman primates.
J Pharmacol Sci
; 120(3): 254-7, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-23076129
8.
Synthesis and in vivo evaluation of [O-methyl-11C] N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide as an imaging probe for 5-HT6 receptors.
Bioorg Med Chem
; 19(17): 5255-9, 2011 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21821420
9.
Biodistribution, toxicology, and radiation dosimetry of 5-HT1A-receptor agonist positron emission tomography ligand [11C]CUMI-101.
Int J Toxicol
; 30(6): 611-8, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21994241
10.
Synthesis and in vivo evaluation of [11C]MPTQ: a potential PET tracer for alpha2A-adrenergic receptors.
Bioorg Med Chem Lett
; 20(12): 3654-7, 2010 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20529687
11.
Synthesis, in vitro and in vivo evaluation of [11C]MMTP: a potential PET ligand for mGluR1 receptors.
Bioorg Med Chem Lett
; 20(12): 3499-501, 2010 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20494576
12.
Modeling considerations for 11C-CUMI-101, an agonist radiotracer for imaging serotonin 1A receptor in vivo with PET.
J Nucl Med
; 49(4): 587-96, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18344443
13.
Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.
J Med Chem
; 49(1): 125-34, 2006 Jan 12.
Artigo
Inglês
| MEDLINE | ID: mdl-16392798
14.
Synthesis and in vivo evaluation of [O-methyl-11C](2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-1-methylpyrrolidine as a 5-HT2A receptor PET ligand.
Nucl Med Biol
; 33(4): 565-74, 2006 May.
Artigo
Inglês
| MEDLINE | ID: mdl-16720250
15.
In vitro and in vivo evaluation of [11C]MPEPy as a potential PET ligand for mGlu5 receptors.
Nucl Med Biol
; 33(8): 1021-7, 2006 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-17127176
16.
Autoradiographic Evaluation of [(18)F]FECUMI-101, a High Affinity 5-HT1AR Ligand in Human Brain.
ACS Med Chem Lett
; 7(5): 482-6, 2016 May 12.
Artigo
Inglês
| MEDLINE | ID: mdl-27190597
17.
Intramolecular Cyclization of Azides by Iminium Species. A Novel Method for the Construction of Nitrogen Heterocycles under Vilsmeier Conditions.
J Org Chem
; 63(21): 7136-7142, 1998 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-11672351
18.
One-Pot Synthesis of Heterocyclic beta-Chlorovinyl Aldehydes Using Vilsmeier Reagent.
J Org Chem
; 61(19): 6523-6525, 1996 Sep 20.
Artigo
Inglês
| MEDLINE | ID: mdl-11667515
19.
PET and SPECT tracers for glutamate receptors.
Drug Discov Today
; 18(3-4): 173-84, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23092894
20.
Autoradiographic evaluation of [3H]CUMI-101, a novel, selective 5-HT1AR ligand in human and baboon brain.
Brain Res
; 1507: 11-8, 2013 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-23454434