Detalhe da pesquisa
1.
Preclinical evaluation of the epithelial sodium channel inhibitor AZD5634 and implications on human translation.
Am J Physiol Lung Cell Mol Physiol
; 323(5): L536-L547, 2022 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36098422
2.
INEXAS: A Phase 2 Randomized Trial of On-demand Inhaled Interferon Beta-1a in Severe Asthmatics.
Clin Exp Allergy
; 51(2): 273-283, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33091192
3.
Neutrophil extracellular trap formation is regulated by CXCR2 in COPD neutrophils.
Eur Respir J
; 51(4)2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29449427
4.
The chemokine CXCR2 antagonist (AZD5069) preserves neutrophil-mediated host immunity in non-human primates.
Haematologica
; 102(2): e65-e68, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27742769
5.
Effects of the CXCR2 antagonist AZD5069 on lung neutrophil recruitment in asthma.
Pulm Pharmacol Ther
; 45: 121-123, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28549850
6.
AZD5634, an inhaled ENaC inhibitor, in healthy subjects and patients with cystic fibrosis.
J Cyst Fibros
; 21(4): 684-690, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35227647
7.
New generation ENaC inhibitors detach cystic fibrosis airway mucus bundles via sodium/hydrogen exchanger inhibition.
Eur J Pharmacol
; 904: 174123, 2021 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33974881
8.
NETopathic Inflammation in Chronic Obstructive Pulmonary Disease and Severe Asthma.
Front Immunol
; 10: 47, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30804927
9.
Pharmacokinetics of the Oral Selective CXCR2 Antagonist AZD5069: A Summary of Eight Phase I Studies in Healthy Volunteers.
Drugs R D
; 18(2): 149-159, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29856004
10.
Targets of Neutrophil Influx and Weaponry: Therapeutic Opportunities for Chronic Obstructive Airway Disease.
J Immunol Res
; 2017: 5273201, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28596972
11.
Indications for percutaneous endoscopic gastrostomy and survival in old adults.
Food Nutr Res
; 552011.
Artigo
Inglês
| MEDLINE | ID: mdl-21799666