Detalhe da pesquisa
1.
Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity.
Nucleic Acids Res
; 48(4): 1800-1810, 2020 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-31930333
2.
Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms.
PLoS Comput Biol
; 16(9): e1008191, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32970665
3.
High-Content Screening Identifies Src Family Kinases as Potential Regulators of AR-V7 Expression and Androgen-Independent Cell Growth.
Prostate
; 77(1): 82-93, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27699828
4.
Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns.
Methods
; 96: 75-84, 2016 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26521976
5.
A novel ERß high throughput microscopy platform for testing endocrine disrupting chemicals.
Heliyon
; 10(1): e23119, 2024 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38169792
6.
SPACe (Swift Phenotypic Analysis of Cells): an open-source, single cell analysis of Cell Painting data.
bioRxiv
; 2024 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38585902
7.
Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta.
iScience
; 27(3): 109275, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38469564
8.
Gene transcription regulation by ER at the single cell and allele level.
Steroids
; 200: 109313, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37758052
9.
Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures.
iScience
; 25(10): 105200, 2022 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36238893
10.
Quality Control for Single Cell Imaging Analytics Using Endocrine Disruptor-Induced Changes in Estrogen Receptor Expression.
Environ Health Perspect
; 130(2): 27008, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35167326
11.
Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-α.
iScience
; 24(11): 103227, 2021 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34712924
12.
Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.
Mol Cell Biol
; 27(19): 6913-32, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17646391
13.
Single Cell Analysis Of Transcriptionally Active Alleles By Single Molecule FISH.
J Vis Exp
; (163)2020 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33016938
14.
Single-Cell Distribution Analysis of AR Levels by High-Throughput Microscopy in Cell Models: Application for Testing Endocrine-Disrupting Chemicals.
SLAS Discov
; 25(7): 684-694, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32552291
15.
A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals.
SLAS Discov
; 25(7): 695-708, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32392092
16.
Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells.
PLoS One
; 14(11): e0224405, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31710612
17.
Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis.
PLoS One
; 12(7): e0180141, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28704378
18.
High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator.
Oncotarget
; 7(13): 16962-74, 2016 Mar 29.
Artigo
Inglês
| MEDLINE | ID: mdl-26918604
19.
Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays.
Chem Biol
; 21(6): 743-53, 2014 Jun 19.
Artigo
Inglês
| MEDLINE | ID: mdl-24856822
20.
Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis.
PLoS One
; 8(2): e55511, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23405163