Detalhe da pesquisa
1.
In Silico Method Development of Achiral and Chiral Tandem Column Reversed-phase Liquid Chromatography for Multicomponent Pharmaceutical Mixtures.
Anal Chem
; 94(9): 4065-4071, 2022 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35199987
2.
Deuterated Modifiers in Sub/Supercritical Fluid Chromatography for Streamlined NMR Structure Elucidation.
Anal Chem
; 94(35): 12176-12184, 2022 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36001377
3.
Selective Plate-Based Assay for Trace EDTA Analysis via Boron Trifluoride-methanol Derivatization UHPLC-QqQ-MS/MS Enabling Biologic and Vaccine Processes.
Anal Chem
; 94(3): 1678-1685, 2022 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34928586
4.
Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays.
Anal Chem
; 94(3): 1804-1812, 2022 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34931812
5.
Automated Hydrophobic Interaction Chromatography Screening Combined with In Silico Optimization as a Framework for Nondenaturing Analysis and Purification of Biopharmaceuticals.
Anal Chem
; 94(49): 17131-17141, 2022 12 13.
Artigo
Inglês
| MEDLINE | ID: mdl-36441925
6.
In situ real time monitoring of emulsification and homogenization processes for vaccine adjuvants.
Analyst
; 147(3): 378-386, 2022 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-34908043
7.
Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets.
Anal Bioanal Chem
; 414(12): 3581-3591, 2022 May.
Artigo
Inglês
| MEDLINE | ID: mdl-35441858
8.
Dual-Gradient Unified Chromatography: A New Paradigm for Versatility in Simultaneous Multicomponent Analysis.
Angew Chem Int Ed Engl
; 61(45): e202208854, 2022 11 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36111975
9.
Trapping-Enrichment Multi-dimensional Liquid Chromatography with On-Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale.
Angew Chem Int Ed Engl
; 61(21): e202117655, 2022 05 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35139257
10.
In Silico Multifactorial Modeling for Streamlined Development and Optimization of Two-Dimensional Liquid Chromatography.
Anal Chem
; 93(33): 11532-11539, 2021 08 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34375071
11.
Mapping the Separation Landscape in Two-Dimensional Liquid Chromatography: Blueprints for Efficient Analysis and Purification of Pharmaceuticals Enabled by Computer-Assisted Modeling.
Anal Chem
; 93(2): 964-972, 2021 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33301312
12.
The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances.
Acc Chem Res
; 52(7): 1990-2002, 2019 07 16.
Artigo
Inglês
| MEDLINE | ID: mdl-31198042
13.
Mass Activated Droplet Sorting (MADS) Enables High-Throughput Screening of Enzymatic Reactions at Nanoliter Scale.
Angew Chem Int Ed Engl
; 59(11): 4470-4477, 2020 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31868984
14.
Chaotropic Effects in Sub/Supercritical Fluid Chromatography via Ammonium Hydroxide in Water-Rich Modifiers: Enabling Separation of Peptides and Highly Polar Pharmaceuticals at the Preparative Scale.
Anal Chem
; 91(21): 13907-13915, 2019 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31549812
15.
Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug substances.
Analyst
; 144(9): 2872-2880, 2019 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30830135
16.
Assessment of coulometric array electrochemical detection coupled with HPLC-UV for the absolute quantitation of pharmaceuticals.
Analyst
; 142(3): 525-536, 2017 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28098264
17.
Using Electron Paramagnetic Resonance Spectroscopy To Facilitate Problem Solving in Pharmaceutical Research and Development.
J Org Chem
; 81(16): 6937-44, 2016 08 19.
Artigo
Inglês
| MEDLINE | ID: mdl-27322370
18.
A Mild Cu(I)-Catalyzed Oxidative Aromatization of Indolines to Indoles.
J Org Chem
; 81(20): 10009-10015, 2016 10 21.
Artigo
Inglês
| MEDLINE | ID: mdl-27700080
19.
Asymmetric synthesis of cyclic indole aminals via 1,3-stereoinduction.
J Org Chem
; 79(18): 8533-40, 2014 Sep 19.
Artigo
Inglês
| MEDLINE | ID: mdl-25162915
20.
Real-time in situ monitoring of CRM-197 and polysaccharide conjugation reaction by fluorescence spectroscopy.
Bioanalysis
; 15(9): 493-501, 2023 May.
Artigo
Inglês
| MEDLINE | ID: mdl-37141441