Detalhe da pesquisa
1.
Truncation of the constant domain drives amyloid formation by immunoglobulin light chains.
J Biol Chem
; 300(4): 107174, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38499153
2.
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence.
J Pathol
; 255(3): 311-318, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34331462
3.
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils.
J Biol Chem
; 295(33): 11379-11387, 2020 08 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32571879
4.
Diagnostic amyloid proteomics: experience of the UK National Amyloidosis Centre.
Clin Chem Lab Med
; 58(6): 948-957, 2020 06 25.
Artigo
Inglês
| MEDLINE | ID: mdl-32069225
5.
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
J Biol Chem
; 293(37): 14192-14199, 2018 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30018138
6.
Co-fibrillogenesis of Wild-type and D76N ß2-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS.
J Biol Chem
; 291(18): 9678-89, 2016 Apr 29.
Artigo
Inglês
| MEDLINE | ID: mdl-26921323
7.
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proc Natl Acad Sci U S A
; 111(4): 1539-44, 2014 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-24474780
8.
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
J Biol Chem
; 290(4): 2395-404, 2015 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-25505181
9.
Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic ß2-microglobulin.
J Biol Chem
; 289(6): 3318-27, 2014 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24338476
10.
Capillary electrophoresis analysis of different variants of the amyloidogenic protein ß2 -microglobulin as a simple tool for misfolding and stability studies.
Electrophoresis
; 36(19): 2465-72, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26084573
11.
Monitoring the interaction between ß2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates ß2-microglobulin oligomers.
J Biol Chem
; 288(24): 17844-58, 2013 Jun 14.
Artigo
Inglês
| MEDLINE | ID: mdl-23645685
12.
Structure, folding dynamics, and amyloidogenesis of D76N ß2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin.
J Biol Chem
; 288(43): 30917-30, 2013 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-24014031
13.
Degradation versus fibrillogenesis, two alternative pathways modulated by seeds and glycosaminoglycans.
Protein Sci
; 33(3): e4931, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38380705
14.
Human wild-type and D76N ß2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans.
FASEB Bioadv
; 5(11): 484-505, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37936921
15.
Calcium Binds to Transthyretin with Low Affinity.
Biomolecules
; 12(8)2022 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36008960
16.
Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms.
Front Mol Biosci
; 9: 830006, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35237660
17.
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis.
Nat Commun
; 12(1): 7112, 2021 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34876572
18.
Proteomic Analysis for the Diagnosis of Fibrinogen Aα-chain Amyloidosis.
Kidney Int Rep
; 4(7): 977-986, 2019 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-31317119
19.
Binding of Monovalent and Bivalent Ligands by Transthyretin Causes Different Short- and Long-Distance Conformational Changes.
J Med Chem
; 62(17): 8274-8283, 2019 09 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31393717
20.
The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis.
J Pathol Clin Res
; 5(3): 145-153, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30740936