Detalhe da pesquisa
1.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
PLoS Genet
; 17(1): e1009224, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33417599
2.
Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation.
Bioinformatics
; 35(14): i568-i576, 2019 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31510680
3.
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Nature
; 502(7471): 377-80, 2013 Oct 17.
Artigo
Inglês
| MEDLINE | ID: mdl-23995691
4.
Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.
Crit Care Med
; 46(6): 915-925, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29537985
5.
HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism.
Hum Mol Genet
; 23(2): 319-32, 2014 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24001602
6.
Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs.
PLoS Genet
; 9(8): e1003649, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23935528
7.
Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism.
Arterioscler Thromb Vasc Biol
; 34(9): 1917-23, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-25035345
8.
Mangravite et al. reply.
Nature
; 513(7518): E3, 2014 Sep 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25230670
9.
RHOA is a modulator of the cholesterol-lowering effects of statin.
PLoS Genet
; 8(11): e1003058, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-23166513
10.
Genetic and multi-omic risk assessment of Alzheimer's disease implicates core associated biological domains.
Alzheimers Dement (N Y)
; 10(2): e12461, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38650747
11.
Open drug discovery in Alzheimer's disease.
Alzheimers Dement (N Y)
; 9(2): e12394, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37215505
12.
A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.
Pharmacogenet Genomics
; 22(11): 796-802, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-23047291
13.
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
Sci Rep
; 12(1): 6117, 2022 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35413975
14.
Remote smartphone monitoring of Parkinson's disease and individual response to therapy.
Nat Biotechnol
; 40(4): 480-487, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34373643
15.
Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.
Front Aging Neurosci
; 14: 857628, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35197847
16.
Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source.
J Nutr
; 141(12): 2180-5, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22031660
17.
Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.
Arterioscler Thromb Vasc Biol
; 30(7): 1485-92, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20413733
18.
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins.
Proc Natl Acad Sci U S A
; 105(38): 14561-6, 2008 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-18794527
19.
Smartphone-Based VO2max Measurement With Heart Snapshot in Clinical and Real-world Settings With a Diverse Population: Validation Study.
JMIR Mhealth Uhealth
; 9(6): e26006, 2021 06 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34085945
20.
Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease.
Genome Med
; 13(1): 76, 2021 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33947463