Detalhe da pesquisa
1.
IL-23 regulation of myeloid cell biology during inflammation.
Cytokine
; 179: 156619, 2024 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38669908
2.
Role of macrophages in the fibrotic phase of rat crescentic glomerulonephritis.
Am J Physiol Renal Physiol
; 304(8): F1043-53, 2013 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23408165
3.
Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors.
Bioorg Med Chem Lett
; 23(23): 6363-9, 2013 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24138939
4.
Matrix metalloproteinase-9 inhibition reduces inflammation and improves motility in murine models of postoperative ileus.
Gastroenterology
; 141(4): 1283-92, 1292.e1-4, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21703213
5.
c-fms blockade reverses glomerular macrophage infiltration and halts development of crescentic anti-GBM glomerulonephritis in the rat.
Lab Invest
; 91(7): 978-91, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-21519331
6.
Reducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitors.
Bioorg Med Chem Lett
; 20(13): 3925-9, 2010 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20570147
7.
The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis.
PLoS One
; 14(11): e0223918, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31710624
8.
Reproducing human and cross-species drug toxicities using a Liver-Chip.
Sci Transl Med
; 11(517)2019 11 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31694927
9.
Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors.
Bioorg Med Chem Lett
; 18(7): 2355-61, 2008 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18342505
10.
Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor.
Bioorg Med Chem Lett
; 18(6): 1926-30, 2008 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18308567
11.
Discovery of novel FMS kinase inhibitors as anti-inflammatory agents.
Bioorg Med Chem Lett
; 18(5): 1642-8, 2008 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18242992
12.
Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors.
Bioorg Med Chem Lett
; 18(6): 2097-102, 2008 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18289848
13.
Structure-based optimization of a potent class of arylamide FMS inhibitors.
Bioorg Med Chem Lett
; 18(12): 3632-7, 2008 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-18495479
14.
Identification of novel short chain 4-substituted indoles as potent alphavbeta3 antagonist using structure-based drug design.
Eur J Med Chem
; 42(3): 334-43, 2007 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-17184884
15.
Novel potent and selective alphavbeta3/alphavbeta5 integrin dual antagonists with reduced binding affinity for human serum albumin.
Eur J Med Chem
; 41(7): 847-61, 2006 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-16697080
16.
Targeting c-fms kinase attenuates chronic aristolochic acid nephropathy in mice.
Oncotarget
; 7(10): 10841-56, 2016 Mar 08.
Artigo
Inglês
| MEDLINE | ID: mdl-26909597
17.
Design, synthesis, and biological evaluation of novel potent and selective alphavbeta3/alphavbeta5 integrin dual inhibitors with improved bioavailability. Selection of the molecular core.
J Med Chem
; 48(4): 926-34, 2005 Feb 24.
Artigo
Inglês
| MEDLINE | ID: mdl-15715463
18.
2-Hydroxy-4,6-diamino-[1,3,5]triazines: a novel class of VEGF-R2 (KDR) tyrosine kinase inhibitors.
J Med Chem
; 48(6): 1717-20, 2005 Mar 24.
Artigo
Inglês
| MEDLINE | ID: mdl-15771417
19.
Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.
J Med Chem
; 48(4): 909-12, 2005 Feb 24.
Artigo
Inglês
| MEDLINE | ID: mdl-15715460
20.
A functional radioreceptor assay of alpha-V-beta-3 (alphavbeta3) inhibitors in plasma: application as an ex vivo pharmacodynamic model.
J Biochem Biophys Methods
; 65(2-3): 107-20, 2005 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-16325916