Detalhe da pesquisa
1.
Efficient, multi-hundred-gram scale access to E3 ubiquitin ligase ligands for degrader development.
Org Biomol Chem
; 21(41): 8344-8352, 2023 10 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37800999
2.
Scale-up and optimization of the synthesis of dual CBP/BRD4 inhibitor ISOX-DUAL.
Org Biomol Chem
; 20(19): 4021-4029, 2022 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35506991
3.
Solution Structure and Conformational Dynamics of a Doublet Acyl Carrier Protein from Prodigiosin Biosynthesis.
Biochemistry
; 60(3): 219-230, 2021 01 26.
Artigo
Inglês
| MEDLINE | ID: mdl-33416314
4.
Application of the Exactive Plus EMR for automated protein-ligand screening by non-covalent mass spectrometry.
Rapid Commun Mass Spectrom
; 28(13): 1561-8, 2014 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24861608
5.
Identification of differential protein binding affinities in an atropisomeric pharmaceutical compound by noncovalent mass spectrometry, equilibrium dialysis, and nuclear magnetic resonance.
Anal Chem
; 85(12): 5958-64, 2013 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23697870
6.
Developing, Choosing, and Using the Chemical Toolbox for Infectious Diseases Research.
ACS Infect Dis
; 9(1): 2-4, 2023 01 13.
Artigo
Inglês
| MEDLINE | ID: mdl-36511756
7.
Chirality: a key parameter in chemical probes.
RSC Chem Biol
; 4(10): 716-721, 2023 Oct 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37799583
8.
Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease.
J Med Chem
; 65(19): 13328-13342, 2022 10 13.
Artigo
Inglês
| MEDLINE | ID: mdl-36179320
9.
Analysis of Streptomyces coelicolor phosphopantetheinyl transferase, AcpS, reveals the basis for relaxed substrate specificity.
Biochemistry
; 50(25): 5704-17, 2011 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21595442
10.
Reviewing the toolbox for degrader development in oncology.
Curr Opin Pharmacol
; 59: 43-51, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34058637
11.
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma.
Oncogenesis
; 10(10): 68, 2021 Oct 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34642317
12.
Developing degraders: principles and perspectives on design and chemical space.
Medchemcomm
; 10(10): 1755-1764, 2019 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31867093
13.
The Effect of Pre-Analytical Conditions on Blood Metabolomics in Epidemiological Studies.
Metabolites
; 9(4)2019 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30987180
14.
Automated protein-ligand interaction screening by mass spectrometry.
J Med Chem
; 55(2): 837-51, 2012 Jan 26.
Artigo
Inglês
| MEDLINE | ID: mdl-22148839