RESUMO
In 1996-97, the last dengue virus serotype 2 (DENV-2) outbreak occurred in French Polynesia. In February 2019, DENV-2 infection was detected in a traveller from New Caledonia. In March, autochthonous DENV-2 infection was diagnosed in two residents. A DENV-2 outbreak was declared on 10 April with 106 cases as at 24 June. Most of the population is not immune to DENV-2; a large epidemic could occur with risk of imported cases in mainland France.
Assuntos
Vírus da Dengue/genética , Vírus da Dengue/isolamento & purificação , Dengue/diagnóstico , Surtos de Doenças , Mosquitos Vetores/virologia , RNA Viral/genética , Adolescente , Adulto , Animais , Dengue/epidemiologia , Feminino , Hospitalização , Humanos , Masculino , Pessoa de Meia-Idade , Filogenia , Polinésia/epidemiologia , Reação em Cadeia da Polimerase em Tempo Real , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Sorogrupo , Adulto JovemRESUMO
We investigated dengue and chikungunya virus antibody seroprevalence in French Polynesia during 2014-2015. Dengue virus seroprevalence was ≈60% among schoolchildren and >83% among the general population; chikungunya virus seroprevalence was <3% before and 76% after Zika virus emergence (2013). Dengue virus herd immunity may affect Zika virus infection and pathogenesis.
Assuntos
Anticorpos Antivirais/imunologia , Febre de Chikungunya/epidemiologia , Febre de Chikungunya/imunologia , Vírus Chikungunya/imunologia , Vírus da Dengue/imunologia , Dengue/epidemiologia , Dengue/imunologia , Adolescente , Adulto , Anticorpos Neutralizantes/imunologia , Febre de Chikungunya/história , Criança , Pré-Escolar , Dengue/história , História do Século XXI , Humanos , Pessoa de Meia-Idade , Testes de Neutralização , Polinésia/epidemiologia , Estudos Soroepidemiológicos , Adulto JovemRESUMO
In French Polynesia, the four serotypes of dengue virus (DENV-1 to -4) have caused 14 epidemics since the mid-1940s. From the end of 2016, an increasing number of Pacific Island Countries and Territories have reported DENV-2 outbreaks and in February 2017, DENV-2 infection was detected in French Polynesia in three travellers from Vanuatu. As DENV-2 has not been circulating in French Polynesia since December 2000, there is high risk for an outbreak to occur.