Detalhe da pesquisa
1.
Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.
Cell
; 162(1): 33-44, 2015 Jul 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26140591
2.
PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism.
Genes Dev
; 32(15-16): 1035-1044, 2018 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30006480
3.
Integrator regulates transcriptional initiation and pause release following activation.
Mol Cell
; 56(1): 128-139, 2014 Oct 02.
Artigo
Inglês
| MEDLINE | ID: mdl-25201415
4.
Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers.
Genes Dev
; 28(9): 1018-28, 2014 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24788520
5.
A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses.
J Biol Chem
; 286(3): 1938-50, 2011 Jan 21.
Artigo
Inglês
| MEDLINE | ID: mdl-21097508
6.
MEKK4 sequesters RIP2 to dictate NOD2 signal specificity.
Curr Biol
; 18(18): 1402-8, 2008 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-18775659
7.
Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity.
Nat Med
; 25(3): 507-516, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30842678
8.
Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer.
ACS Med Chem Lett
; 10(6): 857-862, 2019 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31223438
9.
RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Cancer Cell
; 34(5): 757-774.e7, 2018 11 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30423296
10.
Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium.
J Exp Med
; 214(12): 3687-3705, 2017 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29089374
11.
RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Cancer Cell
; 38(4): 585-590, 2020 Oct 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33049209
12.
Innate immune-directed NF-κB signaling requires site-specific NEMO ubiquitination.
Cell Rep
; 4(2): 352-61, 2013 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-23871670
13.
IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.
Mol Cell Biol
; 32(13): 2479-89, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22547678
14.
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.
Curr Biol
; 19(15): 1255-63, 2009 Aug 11.
Artigo
Inglês
| MEDLINE | ID: mdl-19592251