Detalhe da pesquisa
1.
Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment.
Proc Natl Acad Sci U S A
; 119(15): e2120003119, 2022 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35377795
2.
Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling.
J Immunol
; 205(3): 731-740, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32571840
3.
Improving in vivo assays in snake venom and antivenom research: A community discussion.
F1000Res
; 13: 192, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38708289
4.
African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages.
BMJ Glob Health
; 9(3)2024 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38485142
5.
Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis.
Front Microbiol
; 15: 1346068, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38362501
6.
A mouse infection model and long-term lymphatic endothelium co-culture system to evaluate drugs against adult Brugia malayi.
PLoS Negl Trop Dis
; 16(6): e0010474, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35671324
7.
NKp46+ natural killer cells develop an activated/memory-like phenotype and contribute to innate immunity against experimental filarial infection.
Front Immunol
; 13: 969340, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36238293
8.
In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus.
Toxicon X
; 14: 100118, 2022 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-35321116
9.
Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis.
J Clin Invest
; 131(5)2021 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33434186
10.
Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni.
ACS Infect Dis
; 7(5): 1260-1274, 2021 05 14.
Artigo
Inglês
| MEDLINE | ID: mdl-33797218
11.
Novel anti-Wolbachia drugs, a new approach in the treatment and prevention of veterinary filariasis?
Vet Parasitol
; 279: 109057, 2020 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-32126342
12.
Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models.
Sci Rep
; 8(1): 5910, 2018 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29651095