Detalhe da pesquisa
1.
Targeting dihydroceramide desaturase 1 (Des1): Syntheses of ceramide analogues with a rigid scaffold, inhibitory assays, and AlphaFold2-assisted structural insights reveal cyclopropenone PR280 as a potent inhibitor.
Bioorg Chem
; 145: 107233, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38422591
2.
Probing Site-Selective Conjugation Chemistries for the Construction of Homogeneous Synthetic Glycodendriproteins.
Chembiochem
; 23(10): e202200020, 2022 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35322922
3.
Revealing 2-dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as sphingosine kinase 2 inhibitors: Some hints on the structural basis for selective inhibition.
Bioorg Chem
; 121: 105668, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35219046
4.
Enantioselective Synthesis of 3-Heterosubstituted-2-amino-1-ols by Sequential Metal-Free Diene Aziridination/Kinetic Resolution.
Chemistry
; 25(54): 12628-12635, 2019 Sep 25.
Artigo
Inglês
| MEDLINE | ID: mdl-31283057
5.
Enantioselective Synthesis of Aminodiols by Sequential Rhodium-Catalysed Oxyamination/Kinetic Resolution: Expanding the Substrate Scope of Amidine-Based Catalysis.
Chemistry
; 24(18): 4635-4642, 2018 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-29341304
6.
Fluorinated triazole-containing sphingosine analogues. Syntheses and in vitro evaluation as SPHK inhibitors.
Org Biomol Chem
; 16(39): 7230-7235, 2018 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30255187
7.
Chemical Access to d-Sarmentose Units Enables the Total Synthesis of Cardenolide Monoglycoside N-1 from Nerium oleander.
J Org Chem
; 82(6): 3327-3333, 2017 03 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28233998
8.
Palladium-catalyzed allylic amination: a powerful tool for the enantioselective synthesis of acyclic nucleoside phosphonates.
Org Biomol Chem
; 15(34): 7227-7234, 2017 Aug 30.
Artigo
Inglês
| MEDLINE | ID: mdl-28816328
9.
Enantioselective Formal Synthesis of Nectrisine Using a Palladium-Catalyzed Asymmetric Allylic Amination and Cross-Metathesis as Key Steps.
J Org Chem
; 81(12): 5217-21, 2016 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27182738
10.
Chemo-, regio-, and stereoselective silver-catalyzed aziridination of dienes: scope, mechanistic studies, and ring-opening reactions.
J Am Chem Soc
; 136(14): 5342-50, 2014 Apr 09.
Artigo
Inglês
| MEDLINE | ID: mdl-24621209
11.
Tuning the stereoelectronic properties of 1-sulfanylhex-1-enitols for the sequential stereoselective synthesis of 2-deoxy-2-iodo-ß-D-allopyranosides.
J Org Chem
; 79(7): 3060-8, 2014 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-24611618
12.
Advances in the enantioselective synthesis of carbocyclic nucleosides.
Chem Soc Rev
; 42(12): 5056-72, 2013 Jun 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23471263
13.
Sequential directed epoxydation-acidolysis from glycals with MCPBA. A flexible approach to protected glycosyl donors.
J Org Chem
; 76(23): 9622-9, 2011 Dec 02.
Artigo
Inglês
| MEDLINE | ID: mdl-21913684
14.
Short and general procedure for synthesizing cis-1,2-fused 1,3-oxathiolan-, 1,3-oxaselenolan-, and 1,3-oxazolidin-2-imine carbohydrate derivatives.
J Org Chem
; 75(2): 514-7, 2010 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20000787
15.
Asymmetric sulfur ylide based enantioselective synthesis of D-erythro-sphingosine.
Org Biomol Chem
; 6(24): 4502-4, 2008 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-19039356
16.
Stannyl ceramides as efficient acceptors for synthesising beta-galactosyl ceramides.
Org Biomol Chem
; 6(20): 3831-6, 2008 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-18843414
17.
Highly reactive 2-deoxy-2-iodo-d-allo and d-gulo pyranosyl sulfoxide donors ensure ß-stereoselective glycosylations with steroidal aglycones.
RSC Adv
; 8(53): 30076-30079, 2018 Aug 24.
Artigo
Inglês
| MEDLINE | ID: mdl-35546863
18.
Synthesis of carbohydrate-based vinyl selenides via Wittig-type reactions.
Carbohydr Res
; 342(5): 736-43, 2007 Apr 09.
Artigo
Inglês
| MEDLINE | ID: mdl-17258697
19.
Recent advances in the glycosylation of sphingosines and ceramides.
Carbohydr Res
; 342(12-13): 1595-612, 2007 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-17482586
20.
General method for synthesizing pyranoid glycals. A new route to allal and gulal derivatives.
Org Lett
; 8(4): 673-5, 2006 Feb 16.
Artigo
Inglês
| MEDLINE | ID: mdl-16468739