Detalhe da pesquisa
1.
Human PLD structures enable drug design and characterization of isoenzyme selectivity.
Nat Chem Biol
; 16(4): 391-399, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32042197
2.
Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity.
Bioorg Med Chem Lett
; 28(10): 1964-1971, 2018 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29636220
3.
Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids.
Tetrahedron
; 71(37): 6424-6436, 2015 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-26257440
4.
New natural products as new leads for antibacterial drug discovery.
Bioorg Med Chem Lett
; 24(2): 413-8, 2014 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24388805
5.
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke.
J Med Chem
; 67(6): 4676-4690, 2024 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38467640
6.
Empowering Voices: Inspiring Women in Medicinal Chemistry.
ACS Med Chem Lett
; 15(4): 424-431, 2024 Apr 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38628790
7.
Empowering Voices: Inspiring Women in Medicinal Chemistry.
J Med Chem
; 67(6): 4251-4258, 2024 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38456628
8.
Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI).
J Med Chem
; 66(6): 3651-3655, 2023 03 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36884261
9.
Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI).
ACS Med Chem Lett
; 14(4): 345-349, 2023 Apr 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37077389
10.
Discovery of Phospholipase D Inhibitors with Improved Drug-like Properties and Central Nervous System Penetrance.
ACS Med Chem Lett
; 13(4): 665-673, 2022 Apr 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35450377
11.
Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine ß-Lactamases.
J Med Chem
; 63(21): 12511-12525, 2020 11 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32658473
12.
CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling.
Sci Signal
; 11(541)2018 07 31.
Artigo
Inglês
| MEDLINE | ID: mdl-30065029
13.
Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension.
Protein Sci
; 26(2): 152-162, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27727493
14.
Trends and exceptions of physical properties on antibacterial activity for Gram-positive and Gram-negative pathogens.
J Med Chem
; 57(23): 10144-61, 2014 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-25402200