RESUMO
jModelTest is a Java program for the statistical selection of models of nucleotide substitution with thousands of users around the world. For large data sets, the calculations carried out by this program can be too expensive for many users. Here we describe the port of the jModeltest code for Grid computing using DRMAA. This work should facilitate the use of jModelTest on a broad scale.
Assuntos
Redes de Comunicação de Computadores , Evolução Molecular , Modelos Genéticos , Nucleotídeos/genética , SoftwareRESUMO
This work determines the molecular epidemiology of dengue virus in Venezuela by means of phylogenetic calculations performed on the EELA-2 Grid infrastructure with the PhyloGrid application, an open source tool that allows users performing phylogeny reconstruction in their research. In this study, a total of 132 E nucleotide gene sequences of dengue virus from Venezuela recorded in GenBank(R) have been processed in order to reproduce and validate the topology described in the literature.
Assuntos
Variação Antigênica , Redes de Comunicação de Computadores , Vírus da Dengue/genética , Teorema de Bayes , Filogenia , Interface Usuário-Computador , VenezuelaRESUMO
In this work we demonstrate the adequacy of revising the classification systems based on molecular phylogenetic calculations by allowing an arbitrary number of taxas that take advantage of high performance computing platforms for the Human papillomavirus (HPV) case. To do so, we have analysed several phylogenetic trees which have been calculated with the PhyloGrid tool, a workflow developed in the framework of the EELA-2 Project.
Assuntos
Papillomaviridae/genética , Filogenia , Humanos , Papillomaviridae/classificaçãoRESUMO
In the last years an increasing demand for Grid Infrastructures has resulted in several international collaborations. This is the case of the EELA Project, which has brought together collaborating groups of Latin America and Europe. One year ago we presented this e-infrastructure used, among others, by the biomedical groups for the studies of oncological analysis, neglected diseases, sequence alignments and computational phylogenetics. After this period, the achieved advances are summarised in this paper.
Assuntos
Sistemas de Gerenciamento de Base de Dados , Internet , Informática Médica , Comportamento Cooperativo , Europa (Continente) , Humanos , América Latina , Oncologia , Doenças RarasRESUMO
The current demand for Grid Infrastructures to bring collabarating groups between Latina America and Europe has created the EELA proyect. This e-infrastructure is used by Biomedical groups in Latina America and Europe for the studies of ocnological analisis, neglected diseases, sequence alignments and computation plygonetics.