Detalhe da pesquisa
1.
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3.
PLoS Biol
; 21(8): e3002217, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37535677
2.
Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Proc Natl Acad Sci U S A
; 119(5)2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35074873
3.
Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor.
Mol Pharm
; 20(7): 3367-3379, 2023 07 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37260417
4.
Analgesic α-Conotoxin Binding Site on the Human GABAB Receptor.
Mol Pharmacol
; 102(4): 196-208, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35944919
5.
Marine Toxins Targeting Kv1 Channels: Pharmacological Tools and Therapeutic Scaffolds.
Mar Drugs
; 18(3)2020 Mar 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32245015
6.
Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA.
Mar Drugs
; 17(9)2019 Aug 29.
Artigo
Inglês
| MEDLINE | ID: mdl-31470595
7.
NMR Structure of µ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency.
Molecules
; 23(10)2018 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-30360356
8.
Evidence of Cytolysin A nanopore incorporation in mammalian cells assessed by a graphical user interface.
Nanoscale
; 15(42): 16914-16923, 2023 Nov 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37853831
9.
ω-Conotoxin GVIA mimetics that bind and inhibit neuronal Ca(v)2.2 ion channels.
Mar Drugs
; 10(10): 2349-2368, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23170089
10.
µ-Theraphotoxin Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site.
Elife
; 112022 07 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35858123
11.
Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability.
Br J Pharmacol
; 179(1): 179-198, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34599513
12.
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.
Br J Pharmacol
; 179(11): 2631-2646, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34837219
13.
Investigation of CACNA1I Cav3.3 Dysfunction in Hemiplegic Migraine.
Front Mol Neurosci
; 15: 892820, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35928792
14.
In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia.
Stem Cells Transl Med
; 10(8): 1157-1169, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33734599
15.
Small-molecule mimicry hunting strategy in the imperial cone snail, Conus imperialis.
Sci Adv
; 7(11)2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33712468
16.
Modulation of KvAP unitary conductance and gating by 1-alkanols and other surface active agents.
Biophys J
; 98(5): 762-72, 2010 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-20197029
17.
Ketamine inhibits synaptic transmission and nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglia in situ.
Neuropharmacology
; 165: 107932, 2020 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31911104
18.
Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels.
Front Pharmacol
; 11: 633679, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33584315
19.
Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons.
Front Cell Neurosci
; 14: 600895, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33362470
20.
Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom.
Biochem Pharmacol
; 174: 113782, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31881193