Detalhe da pesquisa
1.
Utilization of Photoaffinity Labeling to Investigate Binding of Microtubule Stabilizing Agents to P-Glycoprotein and ß-Tubulin.
J Nat Prod
; 85(3): 720-728, 2022 03 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35240035
2.
Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence.
Mol Pharmacol
; 98(2): 156-167, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32591477
3.
Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners.
J Nat Prod
; 81(3): 607-615, 2018 03 23.
Artigo
Inglês
| MEDLINE | ID: mdl-29522336
4.
Structural Basis of Microtubule Stabilization by Discodermolide.
Chembiochem
; 18(10): 905-909, 2017 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28207984
5.
Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1-dependent.
Proc Natl Acad Sci U S A
; 108(1): 391-6, 2011 Jan 04.
Artigo
Inglês
| MEDLINE | ID: mdl-21173253
6.
Nanoparticle-Encapsulated Doxorubicin Demonstrates Superior Tumor Cell Kill in Triple Negative Breast Cancer Subtypes Intrinsically Resistant to Doxorubicin.
Precis Nanomed
; 1(3): 173-182, 2018 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-31032494
7.
Potentiation of taxol efficacy and by discodermolide in ovarian carcinoma xenograft-bearing mice.
Clin Cancer Res
; 12(1): 298-304, 2006 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16397055
8.
Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants.
Cancer Res
; 65(7): 2854-60, 2005 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-15805287
9.
Therapeutic Advances and New Directions for Triple-Negative Breast Cancer.
Breast Care (Basel)
; 12(1): 21-28, 2017 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-28611537
10.
A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC.
Sci Rep
; 7(1): 1900, 2017 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28507307
11.
Validation of the pharmacodynamics of BMS-247550, an analogue of epothilone B, during a phase I clinical study.
Clin Cancer Res
; 8(7): 2035-43, 2002 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-12114401
12.
Therapies for triple negative breast cancer.
Expert Opin Pharmacother
; 16(7): 983-98, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25881743
13.
High expression of class III ß-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer.
Clin Breast Cancer
; 13(2): 103-8, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23218766
14.
Exploiting MEK inhibitor-mediated activation of ERα for therapeutic intervention in ER-positive ovarian carcinoma.
PLoS One
; 8(2): e54103, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23390495
15.
Characterization of a human ßV-tubulin antibody and expression of this isotype in normal and malignant human tissue.
Cytoskeleton (Hoboken)
; 69(8): 566-76, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22903939
16.
Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence.
Oncotarget
; 2(1-2): 89-98, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21399233
17.
Correction: Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma.
PLoS One
; 11(3): e0151750, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26967738
18.
Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression.
Cancer Res
; 67(23): 11300-8, 2007 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18056456