Detalhe da pesquisa
1.
"Affimer" synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation.
J Biol Chem
; 299(11): 105325, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37805141
2.
Rapid Quantification of C. difficile Glutamate Dehydrogenase and Toxin B (TcdB) with a NanoBiT Split-Luciferase Assay.
Anal Chem
; 94(23): 8156-8163, 2022 06 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35634999
3.
Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications.
Blood
; 133(11): 1233-1244, 2019 03 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30545831
4.
Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk.
Haematologica
; 106(6): 1616-1623, 2021 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32354869
5.
Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action.
Proc Natl Acad Sci U S A
; 115(1): E72-E81, 2018 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29247053
6.
C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W).
Int J Mol Sci
; 21(3)2020 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-32023808
7.
Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli.
Biochemistry
; 57(36): 5301-5314, 2018 09 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30110143
8.
Passive Picoinjection Enables Controlled Crystallization in a Droplet Microfluidic Device.
Small
; 13(41)2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28873281
9.
Exploiting orientation-selective DEER: determining molecular structure in systems containing Cu(ii) centres.
Phys Chem Chem Phys
; 18(8): 5981-94, 2016 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-26837391
10.
Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2.
EMBO J
; 30(2): 417-26, 2011 Jan 19.
Artigo
Inglês
| MEDLINE | ID: mdl-21131908
11.
Probing the molecular mechanisms in copper amine oxidases by generating heterodimers.
Chembiochem
; 16(4): 559-64, 2015 Mar 02.
Artigo
Inglês
| MEDLINE | ID: mdl-25607656
12.
Anti-TNF Thioester Glucocorticoid Antibody-Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model.
J Med Chem
; 2024 May 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38780432
13.
An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases.
Sci Transl Med
; 16(739): eadd8936, 2024 Mar 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38507467
14.
Structure, recombinant expression and mutagenesis studies of the catalase with oxidase activity from Scytalidium thermophilum.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 3): 398-408, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23519415
15.
Investigating the active centre of the Scytalidium thermophilum catalase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 4): 369-75, 2013 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23545640
16.
A urea channel from Bacillus cereus reveals a novel hexameric structure.
Biochem J
; 445(2): 157-66, 2012 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22553922
17.
Optimization of Drug-Linker to Enable Long-term Storage of Antibody-Drug Conjugate for Subcutaneous Dosing.
J Med Chem
; 66(13): 9161-9173, 2023 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37379257
18.
Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC).
J Med Chem
; 66(17): 12544-12558, 2023 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37656698
19.
Recombinant production of the therapeutic peptide lunasin.
Microb Cell Fact
; 11: 28, 2012 Feb 29.
Artigo
Inglês
| MEDLINE | ID: mdl-22376274
20.
Recombinant production of self-assembling ß-structured peptides using SUMO as a fusion partner.
Microb Cell Fact
; 11: 92, 2012 Jul 03.
Artigo
Inglês
| MEDLINE | ID: mdl-22759375