Detalhe da pesquisa
1.
The fibroblast growth factor receptor inhibitor, derazantinib, has strong efficacy in human gastric tumor models and synergizes with paclitaxel in vivo.
Anticancer Drugs
; 34(4): 532-543, 2023 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36729959
2.
Derazantinib, a fibroblast growth factor receptor inhibitor, inhibits colony-stimulating factor receptor-1 in macrophages and tumor cells and in combination with a murine programmed cell death ligand-1-antibody activates the immune environment of murine syngeneic tumor models.
Anticancer Drugs
; 34(9): 1035-1045, 2023 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36729099
3.
Continuous low-dose infusion of patupilone increases the therapeutic index in mouse and rat tumour models.
Anticancer Drugs
; 29(7): 691-701, 2018 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29734209
4.
Tumour T1 changes in vivo are highly predictive of response to chemotherapy and reflect the number of viable tumour cells--a preclinical MR study in mice.
BMC Cancer
; 14: 88, 2014 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-24528602
5.
Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of a single-institution phase I/II trial.
Oncology
; 83(1): 1-9, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22688083
6.
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.
BMC Cancer
; 11: 198, 2011 May 25.
Artigo
Inglês
| MEDLINE | ID: mdl-21612605
7.
Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.
Anticancer Drugs
; 22(1): 58-78, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20890178
8.
Role of the microenvironment for radiosensitization by patupilone.
Clin Cancer Res
; 15(4): 1335-42, 2009 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19228735
9.
mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.
Clin Cancer Res
; 15(5): 1612-22, 2009 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19223496
10.
Probing the Effects of the FGFR-Inhibitor Derazantinib on Vascular Development in Zebrafish Embryos.
Pharmaceuticals (Basel)
; 14(1)2020 Dec 30.
Artigo
Inglês
| MEDLINE | ID: mdl-33396726
11.
Biomarkers for assessment of pharmacologic activity for a vascular endothelial growth factor (VEGF) receptor inhibitor, PTK787/ZK 222584 (PTK/ZK): translation of biological activity in a mouse melanoma metastasis model to phase I studies in patients with advanced colorectal cancer with liver metastases.
Cancer Chemother Pharmacol
; 57(6): 761-71, 2006 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-16172907
12.
Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure.
Clin Cancer Res
; 11(21): 7773-84, 2005 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-16278399
13.
Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.
Cancer Res
; 62(3): 688-95, 2002 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-11830521
14.
Enhanced uptake of ifosfamide into GH3 prolactinomas with hypercapnic hyperoxic gases monitored in vivo by (31)P MRS.
Neoplasia
; 4(6): 539-43, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-12407448
15.
Microtubule stabilising agents and ionising radiation: multiple exploitable mechanisms for combined treatment.
Eur J Cancer
; 49(1): 245-53, 2013 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-22683167
16.
Regulation of VEGF-expression by patupilone and ionizing radiation in lung adenocarcinoma cells.
Lung Cancer
; 73(3): 294-301, 2011 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-21333376
17.
Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model.
Cancer Chemother Pharmacol
; 67(1): 193-200, 2011 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-20512579
18.
Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma.
Mol Cancer Ther
; 10(6): 1007-17, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21487053
19.
Quantified tumor t1 is a generic early-response imaging biomarker for chemotherapy reflecting cell viability.
Clin Cancer Res
; 16(1): 212-25, 2010 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20008843
20.
Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents.
Cancer Chemother Pharmacol
; 65(4): 625-39, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19784839