[Immediate intraoperative cytological diagnosis of tumors of the ovaries]. / Srochnaia suboperatsionnaia tsitologicheskaia diagnostika opukholei iaichnikov.

Suboperative cytological examination of 86 neoplastic and 4 non-tumor lesions of the ovaries was performed. Phase-contrast, supravital and luminescent microscopy and stained smears from different parts of excised tumor were used simultaneously. Ovarian tumors were shown to have definite cytomorphological features which permit identification of benign and malignant tumors and, in most cases, their histological pattern, too. Three degrees of proliferation of epithelium in serous cystadenoma that require different clinical approach, were distinguished. Correct diagnosis was established in 92.2% of cases. This figure amounted to 95.5% (67 patients) in the benign tumor group, while diagnostic errors were made in 4.5% of cases. In the malignancy group those figures were 91.3 and 8.6%, respectively. Suboperative cytological examination can be carried out within 7-10 minutes; it allows to avoid errors in specimen preparation and is of high diagnostic value.

[The frequency of tumor cell detection in the abdominal cavity during combined treatment of rectal cancer]. / Chastota obnaruzheniia opukholevykh kletok v briushnoi polosti pri kombinirovannom lechenii raka priamoi kishki

In 53 patients with rectal cancer, subjected to an intensive preoperative gamma therapy, and 14 patients, treated only surgically, washings from the abdominal cavity obtained intraoperatively were studied cytologically. Cancer cells were detected in every second patient of both groups. The frequency of their detection was conditioned by cancer localization in the rectum and a degree of its intraparietal spread. The data obtained indicate the efficacy of intensive preoperative irradiation that causes a radiation damage of tumor cells disseminated intraabdominally during the operative intervention.

[Cytological diagnosis of nodular hyperplasia and cancer of the prostate]. / Tsitologicheskaia diagnostika nodoznoi giperplazii i raka predstatel'noi zheleze.

The results of histological and cytologic examination of the material obtained from 289 transrectal punction biopsies of the prostate carried out in 278 patients were compared. Smears were prepared from bioptates and stained haematoxylineosin after the method of Papenheim, Papanicolaou modified by A. V. Rudenko and L. K. Koonitsa. They were also treated with acridin orange (1:10,000). The histological examination established cancer in 66, nodose hyperplasia--97, chronic prostatitis--38, tuberculosis--4, fibrosis of prostatic stroma--9 and unaltered tissue in 48 cases. Cancer was suspected in 8 cases, while prostatic tissue was not identified in preparations in 8 cases. The cytological study detected cancer in 73 and chronic prostatitis in 42 cases. Cancer was suspected in 8 cases. No tumor or epithelial elements were identified in 148 and 7 cases, respectively. The cytological diagnosis was valid in 81% and cancer was erroneously diagnosed in 18 cases. Malignancy was not detected in 11 cancer patients. The cytological analysis failed to identify any difference between nodose hyperplasia and unaltered tissue of the prostate. It proved to be able to verify clear- and dark-celled adenocarcinoma as well as small cell and polymorphocellular carcinoma. However, it also failed to identify cribriform carcinoma and anaplastic adenocarcinoma.

[Cytomorphological features of epithelial tumors of the rectum]. / Tsitomorfologicheskie priznaki epitelial'nykh opukhole i priamoi kishki.

The discharge and scraping from tumors of the rectum in 166 patients (cancer--103, simple polyp--32, proliferating polyp--17, villous polyp--5, malignant polyp--9) were studied at a time by means of various methods of cytoanalysis of suspension preparations (phase contrast, luminescent, supravital microscopy) and of smears (Pappenheim's staining, staining with hematoxilin-eosin, Papanicolaou method). On the grounds of the obtained data the phase optic, cytoluminescent and cytomorphologic patterns of various histological forms of cancer and polyps are set forth.